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80267 EDEM3

80267

EDEM3

ER degradation enhancing alpha-mannosidase like protein 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition ER degradation enhancing alpha-mannosidase like protein 3

研究结论

Date Results Publications
2020-01-18 11:36:00 IL8 and EDEM3 gene expression ratio indicates peripheral blood mononuclear cell (PBMC) quality. 30496732
2019-02-09 11:53:00 the mannose-trimming activity of EDEM3 toward the model misfolded substrate, the glycoprotein T-cell receptor alpha locus (TCRalpha), was reconstituted only when ERp46 had established a covalent interaction with EDEM3 29784879
2017-06-24 11:14:00 The data corroborated herein suggest that besides ER residents, EDEM3 interacts also with proteins involved in the ERAD cargo recognition and targeting to degradation translocation into the cytosol, including UBA1 and UBA2 ubiquitinating enzymes. In addition, the results indicate that this network of EDEM3 interactors is highly sensitive to interfering with early ER N-glycan processing. 28366632

名称对应

Type IDs
Synonymous C1orf22
Gene
UniProtKB-ID: EDEM3_HUMAN
UniprotKB: Q9BZQ6
UniParc: UPI0000470A2B, UPI000189A8E9
EMBL: AL117441, BC144149, BC105586, AF288393, AL096819, AK315118, BC016464
Ensembl: ENSG00000116406
KO: hsa:80267
Nucleutide sequences
EMBL-CDS: AAI05587.1, AAG60613.1, CAB55926.1, BAG37573.1, AAH16464.2, AAI44150.1
Ensembl_TRS: ENST00000318130, ENST00000367512
Protein sequencees
Ensembl_PRO: ENSP00000318147, ENSP00000356482
RefSeq: XP_005245556.1, XP_016857886.1, XP_011508315.1, XP_011508314.1, NP_001306889.1, XP_011508316.1, XP_016857887.1, NP_079467.3
Others
UniRef100: UniRef100_Q9BZQ6
UniRef90: UniRef90_Q9BZQ6
UniRef50: UniRef50_Q2HXL6
UniGene: Hs.523811
CCDS: CCDS1363.2

全选

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研究热度

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