| Type | Description |
|---|---|
| Definition | centrosomal protein 63 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:22:00 | [Study on Cep63 expression and apoptosis of thyroid papillary carcinoma cell lines TPC-1]. | 33472304 |
| 2020-08-15 19:08:00 | Requirement of the Cep57-Cep63 Interaction for Proper Cep152 Recruitment and Centriole Duplication. | 32152252 |
| 2019-04-06 11:35:00 | Study shows that Cep63 and Cep152 cooperatively generate a heterotetrameric alpha-helical bundle that functions in conjunction with its neighboring hydrophobic motifs to self-assemble into a higher-order cylindrical architecture capable of recruiting downstream components, including Plk4, a key regulator for centriole duplication. Mutations disrupting the self-assembly abrogate Plk4-mediated centriole duplication. | 30858376 |
| 2016-04-16 10:42:00 | CEP63 is particularly important for brain development and might control the proliferation and migration of cells when those two events need to be highly coordinated. | 26400686 |
| 2015-04-18 10:15:00 | centrosomal Cdk1 signals were strongly diminished in cells treated with Cep63 siRNA when sc-54 was used for Cdk1 labeling | 25643699 |
| Type | IDs |
|---|---|
| Synonymous | SCKL6 |
| Gene |
UniProtKB-ID:
CEP63_HUMAN
UniprotKB:
Q96MT8
UniParc:
UPI000020A2C3,
UPI000006EC93,
UPI000006D2FD,
UPI000006F0DF
EMBL:
AK023448,
BC014050,
BK005503,
BC068997,
AK023738,
AK056465,
CH471052
Ensembl:
ENSG00000182923
KO:
hsa:80254
|
| Nucleutide sequences |
EMBL-CDS:
DAA05503.1,
EAW79137.1,
EAW79141.1,
BAB14578.1,
BAB14662.1,
AAH14050.1,
AAH68997.1,
BAB71192.1,
EAW79140.1,
EAW79138.1,
EAW79136.1,
EAW79139.1
Ensembl_TRS:
ENST00000606977,
ENST00000332047,
ENST00000620544,
ENST00000513612,
ENST00000354446,
ENST00000383229,
ENST00000337090
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000482219,
ENSP00000336524,
ENSP00000346432,
ENSP00000328382,
ENSP00000426129,
ENSP00000372716,
ENSP00000475903
RefSeq:
XP_024309539.1,
NP_001340037.1,
XP_024309536.1,
XP_016862738.1,
XP_024309542.1,
NP_001340051.1,
NP_001035859.1,
XP_016862741.1,
XP_006713823.1,
NP_001340041.1,
XP_005247854.1,
XP_016862736.1,
XP_024309538.1,
NP_001340052.1,
NP_001340053.1,
NP_001340049.1,
XP_005247856.1,
NP_001340040.1,
NP_001340042.1,
NP_001340047.1,
XP_024309544.1,
XP_016862737.1,
NP_001340050.1,
XP_024309545.1,
NP_001340054.1,
XP_005247852.1,
NP_001340046.1,
XP_024309540.1,
NP_001340048.1,
NP_001035843.1,
NP_001340055.1,
NP_079456.2,
XP_024309546.1,
NP_001340038.1,
XP_024309541.1,
XP_024309543.1,
NP_001035842.1,
XP_024309547.1,
XP_024309537.1,
NP_001340039.1
|
| Others |
UniRef100:
UniRef100_Q96MT8
UniRef90:
UniRef90_Q96MT8
UniRef50:
UniRef50_Q96MT8
UniGene:
Hs.443301
CCDS:
CCDS43153.1,
CCDS43154.1,
CCDS3086.1,
CCDS43152.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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