| Type | Description |
|---|---|
| Definition | phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-19 16:30:00 | Somatic mutations of PREX2 gene in patients with hepatocellular carcinoma. | 30796242 |
| 2020-09-19 16:25:00 | MicroRNA-561 Affects Proliferation and Transition Through PTEN/AKT Signaling Pathway by Targeting P-REX2a in NSCLC. | 31711559 |
| 2020-08-22 15:27:00 | CELF2 suppresses non-small cell lung carcinoma growth by inhibiting the PREX2-PTEN interaction. | 31241130 |
| 2018-12-22 11:17:00 | Study demonstrates that miR-637 inhibites melanoma cell proliferation by activation of AKT signaling pathway and induces apoptosis through regulation of Bcl-2/Bax expression via targeting P-REX2a. | 30213289 |
| 2018-04-14 11:42:00 | MiR-338-3p suppresses the TNF-alpha-induced lipogenesis in sebocytes by targeting PREX2a and down-regulating PI3K/AKT signaling. | 28597147 |
| Type | IDs |
|---|---|
| Synonymous | DEP.2, DEPDC2, P-REX2, PPP1R129 |
| Gene |
UniProtKB-ID:
PREX2_HUMAN
UniprotKB:
Q70Z35
UniParc:
UPI0004AC3F6A,
UPI0000375435,
UPI00003761B9
EMBL:
AK024079,
BK005160,
AC103783,
AC011853,
AK294299,
BK005161,
AC104416,
AY508996,
AJ437636,
AY508997,
AK023049
Ensembl:
ENSG00000046889
KO:
hsa:80243
|
| Nucleutide sequences |
EMBL-CDS:
DAA05333.1,
BAG57581.1,
AAS82571.1,
DAA05334.1,
BAB14375.1,
AAS82572.1,
CAD26885.2
Ensembl_TRS:
ENST00000288368
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000288368
RefSeq:
XP_011515914.1,
NP_079446.3,
NP_079146.2
|
| Others |
UniRef100:
UniRef100_Q70Z35
UniRef90:
UniRef90_Q70Z35
UniRef50:
UniRef50_Q70Z35
UniGene:
Hs.591867
CCDS:
CCDS6201.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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