| Type | Description |
|---|---|
| Definition | elongation factor for RNA polymerase II 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 10:30:00 | Suppression of Ell3 expression induced senescence in stem cells by increasing Bcl-2 expression. Unlike the effect of Ell3 suppression, the ectopic expression of Ell3 induces apoptosis of stem cells and induces apoptosis of adjacent cells. | 30654843 |
| 2018-04-28 10:12:00 | Authors demonstrated that ER(alpha), GATA3 and FOXA1 form a transcriptional complex with Ell3 to regulate IL-20 expression in ER(+) breast cancer cells. FOXA1 represses IL-20 expression, whereas GATA3 and ER(alpha) activate it. | 28514748 |
| 2017-10-28 10:56:00 | Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival | 28858629 |
| 2016-11-05 11:43:00 | Ell3 stabilizes p53 following cisplatin treatment via its effects on ubiquitin-dependent and -independent proteasomal degradation pathways in breast cancer cells. | 26540344 |
| 2013-10-26 11:06:00 | Ell3 may play a critical role in promoting oncogenesis in breast cancer by regulating cell proliferation and cancer stem cell properties via the ERK1/2 signaling pathway | 23850691 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
ELL3_HUMAN
UniprotKB:
Q9HB65
UniParc:
UPI0000073384,
UPI00005A683B
EMBL:
BC019293,
AK026290,
AC018512,
BC006548,
CH471082,
AK057528,
AF276512,
AK126384,
CR457358
Ensembl:
ENSG00000128886
KO:
hsa:80237
|
| Nucleutide sequences |
EMBL-CDS:
AAH06548.1,
CAG33639.1,
BAG54320.1,
BAG51928.1,
BAB15432.1,
AAG13463.1,
AAH19293.1,
EAW77238.1
Ensembl_TRS:
ENST00000319359
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000320346
RefSeq:
NP_079441.1
|
| Others |
UniRef100:
UniRef100_Q9HB65
UniRef90:
UniRef90_Q9HB65
UniRef50:
UniRef50_Q9HB65
UniGene:
Hs.706346
CCDS:
CCDS10102.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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