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80228 ORAI2

80228

ORAI2

ORAI calcium release-activated calcium modulator 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition ORAI calcium release-activated calcium modulator 2

研究结论

Date Results Publications
2021-02-20 13:35:00 ORAI2 Down-Regulation Potentiates SOCE and Decreases Abeta42 Accumulation in Human Neuroglioma Cells. 32722509
2020-11-28 13:16:00 Orai-1 and Orai-2 regulate oral cancer cell migration and colonisation by suppressing Akt/mTOR/NF-kappaB signalling. 32882268
2020-05-02 10:42:00 Higher expression of Orai2 was independently associated with a worse prognosis of patients with the classical and mesenchymal subtypes of glioblastoma.A strong association between Orai2 expression and apoptosis, stemness, and an epithelial-mesenchymal transition in the glioblastoma. 31772693
2018-10-06 11:23:00 ORAI1-3, are preferentially expressed in proximal tubular epithelial cells and downregulated in patients with diabetic nephropathy. 29203863
2017-09-09 13:08:00 findings provide evidence for a role for Orai1 and Orai2, in SOCE and migration in the human HL60 promyeloblastic cell line 27865925

名称对应

Type IDs
Synonymous C7orf19, CBCIP2, MEM142B, TMEM142B
Gene
UniProtKB-ID: ORAI2_HUMAN, B4DUB4_HUMAN
UniprotKB: Q96SN7, B4DUB4
UniParc: UPI0000070E55, UPI00017A7DE6
EMBL: BC069270, CR457287, AF258552, AK027639, AC093668, AK300574
Ensembl: ENSG00000160991
KO: hsa:80228
Nucleutide sequences
EMBL-CDS: BAB55256.1, AAG23755.1, CAG33568.1, AAP22351.1, AAH69270.1, AAP22352.1, BAG62276.1
Gene_ORFName: PP1729
Ensembl_TRS: ENST00000611770, ENST00000356387, ENST00000403646, ENST00000473939, ENST00000478730
Protein sequencees
Ensembl_PRO: ENSP00000478113, ENSP00000418140, ENSP00000348752, ENSP00000417928, ENSP00000385489
RefSeq: NP_116220.1, NP_001119812.1, NP_001258747.1, NP_001258748.1
Others
UniRef100: UniRef100_Q96SN7
UniRef90: UniRef90_Q96SN7
UniRef50: UniRef50_Q96SN7
UniGene: Hs.363308, Hs.736659
CCDS: CCDS5722.1

全选

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