| Type | Description |
|---|---|
| Definition | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| Date | Results | Publications |
|---|---|---|
| 2017-05-20 14:20:00 | Because Naa10 is reported to acetylate all amino termini that are devoid of methionine and Naa50 acetylates all other peptides that are followed by methionine | 27484799 |
| 2017-05-13 13:42:00 | co-depletion of NatA, a heterodimeric NAT complex that physically interacts with Naa50, rescues the sister-chromatid cohesion defects and the resulting mitotic arrest caused by Naa50 depletion, indicating that NatA and Naa50 play antagonistic roles in cohesion. | 27422821 |
| 2016-04-16 10:49:00 | The study quantitatively compared the Nt-acetylomes of wild-type yeast S. cerevisiae expressing the endogenous yeast Naa50 (yNaa50), the congenic strain lacking yNaa50, and an otherwise identical strain expressing human Naa50 (hNaa50). | 25886145 |
| 2013-11-12 10:41:00 | Development of the first N-terminal acetyltransferase (NAT) inhibitors, including a specific Naa50 inhibitor. | 23557624 |
| 2013-11-12 08:55:00 | The first description of the human homologue of Nat5p/San, hNAT5, the third component of the human NatA N-alpha-acetyltransferase complex | 16507339 |
| Type | IDs |
|---|---|
| Synonymous | MAK3, NAT13, NAT13P, NAT5, NAT5P, SAN, hNaa50p |
| Gene |
UniProtKB-ID:
NAA50_HUMAN,
E7EQ69_HUMAN
UniprotKB:
Q9GZZ1,
E7EQ69
UniParc:
UPI000003B017,
UPI0000D9A0CF,
UPI000041A0C1
EMBL:
AK023256,
AK023090,
BC012731,
AC108693,
CH471052,
CR749314
Ensembl:
ENSG00000121579
KO:
hsa:80218
|
| Nucleutide sequences |
EMBL-CDS:
BAB14397.1,
EAW79630.1,
AAH12731.1,
EAW79629.1,
BAB14490.1,
CAH18169.1
Ensembl_TRS:
ENST00000240922,
ENST00000493900
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000240922,
ENSP00000417837
RefSeq:
NP_079422.1,
NP_001295374.1
|
| Others |
UniRef100:
UniRef100_E7EQ69,
UniRef100_Q9GZZ1
UniRef90:
UniRef90_Q9GZZ1
UniRef50:
UniRef50_Q9GZZ1
UniGene:
Hs.372378
CCDS:
CCDS2975.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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