| Type | Description |
|---|---|
| Definition | TM2 domain containing 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-04-20 12:42:00 | These findings indicated that the TT genotype and T allele frequencies of TM2D3 rs675436 were associated with an increased risk of Epstein-Barr virus-associated gastric carcinoma, while allele A or G of FGFR2 rs755793 had no effect on the occurrence of Epstein-Barr virus-associated tumors in Chinese Han population. | 29446487 |
| 2017-05-13 21:58:00 | Our results establish a rare TM2D3 variant in association with late-onset Alzheimer's disease susceptibility, and together with prior work suggests possible links to the beta-amyloid cascade | 27764101 |
| 2010-01-21 00:00:00 | Our approach yielded 26 candidate genes differentially expressed between patients (Osteoarthritis) and controls. BLP2 and CIAS1 seem to be trans-regulated, as the absence of allelic expression imbalances suggests. | 16642435 |
| Type | IDs |
|---|---|
| Synonymous | BLP2 |
| Gene |
UniProtKB-ID:
TM2D3_HUMAN,
E7EPS7_HUMAN,
H0YNS4_HUMAN,
B4DLL2_HUMAN
UniprotKB:
Q9BRN9,
E7EPS7,
H0YNS4,
B4DLL2
UniParc:
UPI00001B02BE,
UPI0001AE68E7,
UPI00022F8635,
UPI00001AF707,
UPI00017A75AB
EMBL:
AK026257,
AL512689,
AC090164,
AK297048,
AK315584,
AF353992,
CH471101,
BC006150,
BC008873
Ensembl:
ENSG00000184277
KO:
hsa:80213
|
| Nucleutide sequences |
EMBL-CDS:
AAK35066.1,
AAH06150.1,
CAC21647.1,
AAH08873.1,
EAX02315.1,
BAB15415.1,
BAG37956.1,
BAG59574.1
Ensembl_TRS:
ENST00000333202,
ENST00000347970,
ENST00000428002,
ENST00000559107
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000330433,
ENSP00000327584,
ENSP00000402179,
ENSP00000454131
RefSeq:
NP_001294955.1,
NP_079417.2,
NP_510883.2,
NP_001294889.1
|
| Others |
UniRef100:
UniRef100_E7EPS7,
UniRef100_H0YNS4,
UniRef100_B4DLL2,
UniRef100_Q9BRN9
UniRef90:
UniRef90_Q9BRN9,
UniRef90_H0YNS4
UniRef50:
UniRef50_Q9BRN9,
UniRef50_S4RBG3
UniGene:
Hs.288912
CCDS:
CCDS10392.1,
CCDS10393.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 33060197 |
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science David E Gordon , Joseph Hiatt , Mehdi Bouhaddou , Veronica V Rezelj , Svenja Ulferts , Hannes Braberg , Alexander S Jureka , Kirsten Obernier , Jeffrey Z Guo , Jyoti Batra , Robyn M Kaake , Andrew R Weckstein , Tristan W Owens , Meghna Gupta , Sergei Pourmal , Erron W Titus , Merve Cakir , Margaret Soucheray , Michael McGregor , Zeynep Cakir , Gwendolyn Jang , Matthew J O'Meara , Tia A Tummino , Ziyang Zhang , Helene Foussard , Ajda Rojc , Yuan Zhou , Dmitry Kuchenov , Ruth Hüttenhain , Jiewei Xu , Manon Eckhardt , Danielle L Swaney , Jacqueline M Fabius , Manisha Ummadi , Beril Tutuncuoglu , Ujjwal Rathore , Maya Modak , Paige Haas , Kelsey M Haas , Zun Zar Chi Naing , Ernst H Pulido , Ying Shi , Inigo Barrio-Hernandez , Danish Memon , Eirini Petsalaki , Alistair Dunham , Miguel Correa Marrero , David Burke , Cassandra Koh , Thomas Vallet , Jesus A Silvas , Caleigh M Azumaya , Christian Billesbølle , Axel F Brilot , Melody G Campbell , Amy Diallo , Miles Sasha Dickinson , Devan Diwanji , Nadia Herrera , Nick Hoppe , Huong T Kratochvil , Yanxin Liu , Gregory E Merz , Michelle Moritz , Henry C Nguyen , Carlos Nowotny , Cristina Puchades , Alexandrea N Rizo , Ursula Schulze-Gahmen , Amber M Smith , Ming Sun , Iris D Young , Jianhua Zhao , Daniel Asarnow , Justin Biel , Alisa Bowen , Julian R Braxton , Jen Chen , Cynthia M Chio , Un Seng Chio , Ishan Deshpande , Loan Doan , Bryan Faust , Sebastian Flores , Mingliang Jin , Kate Kim , Victor L Lam , Fei Li , Junrui Li , Yen-Li Li , Yang Li , Xi Liu , Megan Lo , Kyle E Lopez , Arthur A Melo , Frank R Moss , Phuong Nguyen , Joana Paulino , Komal Ishwar Pawar , Jessica K Peters , Thomas H Pospiech , Maliheh Safari , Smriti Sangwan , Kaitlin Schaefer , Paul V Thomas , Aye C Thwin , Raphael Trenker , Eric Tse , Tsz Kin Martin Tsui , Feng Wang , Natalie Whitis , Zanlin Yu , Kaihua Zhang , Yang Zhang , Fengbo Zhou , Daniel Saltzberg , QCRG Structural Biology Consortium , Anthony J Hodder , Amber S Shun-Shion , Daniel M Williams , Kris M White , Romel Rosales , Thomas Kehrer , Lisa Miorin , Elena Moreno , Arvind H Patel , Suzannah Rihn , Mir M Khalid , Albert Vallejo-Gracia , Parinaz Fozouni , Camille R Simoneau , Theodore L Roth , David Wu , Mohd Anisul Karim , Maya Ghoussaini , Ian Dunham , Francesco Berardi , Sebastian Weigang , Maxime Chazal , Jisoo Park , James Logue , Marisa McGrath , Stuart Weston , Robert Haupt , C James Hastie , Matthew Elliott , Fiona Brown , Kerry A Burness , Elaine Reid , Mark Dorward , Clare Johnson , Stuart G Wilkinson , Anna Geyer , Daniel M Giesel , Carla Baillie , Samantha Raggett , Hannah Leech , Rachel Toth , Nicola Goodman , Kathleen C Keough , Abigail L Lind , Zoonomia Consortium , Reyna J Klesh , Kafi R Hemphill , Jared Carlson-Stevermer , Jennifer Oki , Kevin Holden , Travis Maures , Katherine S Pollard , Andrej Sali , David A Agard , Yifan Cheng , James S Fraser , Adam Frost , Natalia Jura , Tanja Kortemme , Aashish Manglik , Daniel R Southworth , Robert M Stroud , Dario R Alessi , Paul Davies , Matthew B Frieman , Trey Ideker , Carmen Abate , Nolwenn Jouvenet , Georg Kochs , Brian Shoichet , Melanie Ott , Massimo Palmarini , Kevan M Shokat , Adolfo GarcÃa-Sastre , Jeremy A Rassen , Robert Grosse , Oren S Rosenberg , Kliment A Verba , Christopher F Basler , Marco Vignuzzi , Andrew A Peden , Pedro Beltrao , Nevan J Krogan |
2020-12-04 | - |
| 32353859 |
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature David E Gordon , Gwendolyn M Jang , Mehdi Bouhaddou , Jiewei Xu , Kirsten Obernier , Kris M White , Matthew J O'Meara , Veronica V Rezelj , Jeffrey Z Guo , Danielle L Swaney , Tia A Tummino , Ruth Hüttenhain , Robyn M Kaake , Alicia L Richards , Beril Tutuncuoglu , Helene Foussard , Jyoti Batra , Kelsey Haas , Maya Modak , Minkyu Kim , Paige Haas , Benjamin J Polacco , Hannes Braberg , Jacqueline M Fabius , Manon Eckhardt , Margaret Soucheray , Melanie J Bennett , Merve Cakir , Michael J McGregor , Qiongyu Li , Bjoern Meyer , Ferdinand Roesch , Thomas Vallet , Alice Mac Kain , Lisa Miorin , Elena Moreno , Zun Zar Chi Naing , Yuan Zhou , Shiming Peng , Ying Shi , Ziyang Zhang , Wenqi Shen , Ilsa T Kirby , James E Melnyk , John S Chorba , Kevin Lou , Shizhong A Dai , Inigo Barrio-Hernandez , Danish Memon , Claudia Hernandez-Armenta , Jiankun Lyu , Christopher J P Mathy , Tina Perica , Kala Bharath Pilla , Sai J Ganesan , Daniel J Saltzberg , Ramachandran Rakesh , Xi Liu , Sara B Rosenthal , Lorenzo Calviello , Srivats Venkataramanan , Jose Liboy-Lugo , Yizhu Lin , Xi-Ping Huang , YongFeng Liu , Stephanie A Wankowicz , Markus Bohn , Maliheh Safari , Fatima S Ugur , Cassandra Koh , Nastaran Sadat Savar , Quang Dinh Tran , Djoshkun Shengjuler , Sabrina J Fletcher , Michael C O'Neal , Yiming Cai , Jason C J Chang , David J Broadhurst , Saker Klippsten , Phillip P Sharp , Nicole A Wenzell , Duygu Kuzuoglu-Ozturk , Hao-Yuan Wang , Raphael Trenker , Janet M Young , Devin A Cavero , Joseph Hiatt , Theodore L Roth , Ujjwal Rathore , Advait Subramanian , Julia Noack , Mathieu Hubert , Robert M Stroud , Alan D Frankel , Oren S Rosenberg , Kliment A Verba , David A Agard , Melanie Ott , Michael Emerman , Natalia Jura , Mark von Zastrow , Eric Verdin , Alan Ashworth , Olivier Schwartz , Christophe d'Enfert , Shaeri Mukherjee , Matt Jacobson , Harmit S Malik , Danica G Fujimori , Trey Ideker , Charles S Craik , Stephen N Floor , James S Fraser , John D Gross , Andrej Sali , Bryan L Roth , Davide Ruggero , Jack Taunton , Tanja Kortemme , Pedro Beltrao , Marco Vignuzzi , Adolfo GarcÃa-Sastre , Kevan M Shokat , Brian K Shoichet , Nevan J Krogan |
2020-07-01 | - |
| 29987050 |
Proc. Natl. Acad. Sci. U.S.A. Tengfei Xiao , Wei Li , Xiaoqing Wang , Han Xu , Jixin Yang , Qiu Wu , Ying Huang , Joseph Geradts , Peng Jiang , Teng Fei , David Chi , Chongzhi Zang , Qi Liao , Jonathan Rennhack , Eran Andrechek , Nanlin Li , Simone Detre , Mitchell Dowsett , Rinath M Jeselsohn , X Shirley Liu , Myles Brown |
2018-07-31 | - |
| 29446487 |
J Med Virol Qianqian Zhang , Wen Liu , Yang Yang , Zhenzhen Zhao , Bing Luo |
2018-06-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 27764101 |
Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease. PLoS Genet Johanna Jakobsdottir , Sven J van der Lee , Joshua C Bis , Vincent Chouraki , David Li-Kroeger , Shinya Yamamoto , Megan L Grove , Adam Naj , Maria Vronskaya , Jose L Salazar , Anita L DeStefano , Jennifer A Brody , Albert V Smith , Najaf Amin , Rebecca Sims , Carla A Ibrahim-Verbaas , Seung-Hoan Choi , Claudia L Satizabal , Oscar L Lopez , Alexa Beiser , M Arfan Ikram , Melissa E Garcia , Caroline Hayward , Tibor V Varga , Samuli Ripatti , Paul W Franks , Göran Hallmans , Olov Rolandsson , Jan-HÃ¥kon Jansson , David J Porteous , Veikko Salomaa , Gudny Eiriksdottir , Kenneth M Rice , Hugo J Bellen , Daniel Levy , Andre G Uitterlinden , Valur Emilsson , Jerome I Rotter , Thor Aspelund , Cohorts for Heart and Aging Research in Genomic Epidemiology consortium , Alzheimerâs Disease Genetic Consortium , Genetic and Environmental Risk in Alzheimerâs Disease consortium , Christopher J O'Donnell , Annette L Fitzpatrick , Lenore J Launer , Albert Hofman , Li-San Wang , Julie Williams , Gerard D Schellenberg , Eric Boerwinkle , Bruce M Psaty , Sudha Seshadri , Joshua M Shulman , Vilmundur Gudnason , Cornelia M van Duijn |
2016-10-01 | - |
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 22990118 |
Charting the landscape of tandem BRCT domain-mediated protein interactions. Sci Signal Nicholas T Woods , Rafael D Mesquita , Michael Sweet , Marcelo A Carvalho , Xueli Li , Yun Liu , Huey Nguyen , C Eric Thomas , Edwin S Iversen , Sylvia Marsillac , Rachel Karchin , John Koomen , Alvaro N A Monteiro |
2012-01-01 |
RANBP9,
DPP3,
G3BP1,
RBM5,
ALYREF,
CDK5,
DCAF7,
SRRM1,
CDK9,
AKAP8,
SF3A1,
NPM3,
ANAPC10,
RACK1,
CD2BP2,
MCRS1,
PPIH,
CAP1,
LRRC41,
UNC13B,
FBLN5,
RPP30,
NPC2,
SMC2,
PAICS,
MYL12A,
CCT6B,
CFL1,
MGEA5,
NUDC,
AHCYL1,
SRSF10,
VAMP5,
RUVBL2,
CPSF4,
SUGT1,
DBF4,
KDELR1,
EBNA1BP2,
CKAP4,
MAPRE2,
COPS5,
IMMT,
ILVBL,
KIF2C,
CPSF6,
DDX52,
SOX30,
WDR5,
HNRNPUL1,
KRR1,
HIBADH,
FGFR1OP,
KIF3A,
CLASRP,
ZWINT,
WDHD1,
STRAP,
WDR6,
DDX20,
XPOT,
COPE,
GPN1,
PHB2,
CBX3,
U2AF2,
EXOSC8,
DTX2,
LACTB,
OSBPL8,
CIRBP,
DIS3L,
AP3S1,
BTBD16,
COMTD1,
PDZD8,
AGAP4,
CLU,
ANAPC16,
CLTC,
LSM12,
ZNF428,
COL1A1,
COL1A2,
SPATA18,
SPATA4,
CREBBP,
ZNF280B,
AAMP,
DNHD1,
CSNK2A1,
CSNK2B,
CARMIL2,
CSRP2,
SLC25A10,
CSTB,
CTBP1,
CTBP2,
COMMD1
|
| 20351267 |
Mig-6 controls EGFR trafficking and suppresses gliomagenesis. Proc Natl Acad Sci U S A Haoqiang Ying , Hongwu Zheng , Kenneth Scott , Ruprecht Wiedemeyer , Haiyan Yan , Carol Lim , Joseph Huang , Sabin Dhakal , Elena Ivanova , Yonghong Xiao , Hailei Zhang , Jian Hu , Jayne M Stommel , Michelle A Lee , An-Jou Chen , Ji-Hye Paik , Oreste Segatto , Cameron Brennan , Lisa A Elferink , Y Alan Wang , Lynda Chin , Ronald A DePinho |
2010-04-13 | - |
| 16642435 |
Cis- and trans-acting gene regulation is associated with osteoarthritis. Am J Hum Genet Sandra Mahr , Gerd-Rüdiger Burmester , Dietmar Hilke , Udo Göbel , Andreas Grützkau , Thomas Häupl , Matthias Hauschild , Dirk Koczan , Veit Krenn , Jasper Neidel , Carsten Perka , Andreas Radbruch , Hans-Jürgen Thiesen , Brigitte Müller |
2006-05-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员