| Type | Description |
|---|---|
| Definition | nucleoporin 214 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 11:36:00 | these findings indicate that CRM1 acts as a key molecule that connects leukemogenic proteins to aberrant HOX gene regulation either via nucleoporin-CRM1 interaction (for SET-Nup214) or NES-CRM1 interaction (for NPM1c). | 31755865 |
| 2020-03-21 12:29:00 | Loss of Nup214 inhibited nuclear export of recombination signal-binding protein for immunoglobulin kappaJ region (RBP-J), the DNA-binding component of the Notch pathway. NUP214 fusion proteins, causative for certain cases of T-cell acute lymphatic leukemia, potentially contribute to tumorigenesis via a Notch-dependent mechanism. | 31186352 |
| 2020-03-14 10:36:00 | Pathogenic Variants in NUP214 Cause "Plugged" Channels and Acute Febrile Encephalopathy. | 31178128 |
| 2019-06-15 10:27:00 | oncogenic kinase NUP214-ABL1, through its downstream effector directly cooperates with TLX1 at the transcriptional level. | 30107177 |
| 2019-03-30 11:53:00 | we propose that while NUP214 complete deficiency may be lethal in humans, partial deficiency results in a novel autosomal recessive disorder characterized by severe encephalopathy and early death. | 30758658 |
| Type | IDs |
|---|---|
| Synonymous | CAIN, CAN |
| Gene |
UniProtKB-ID:
NU214_HUMAN,
B7ZAV2_HUMAN
UniprotKB:
P35658,
B7ZAV2
UniParc:
UPI000178DE71,
UPI00005C302E,
UPI000178DE72,
UPI000006F2A9,
UPI00001BBB2F,
UPI000191548D
EMBL:
BC105998,
AL157938,
X64228,
BC045620,
AB159230,
D14689,
AK316417
Ensembl:
ENSG00000126883
KO:
hsa:8021
|
| Nucleutide sequences |
EMBL-CDS:
BAD07398.1,
AAI05999.1,
CAA45535.1,
AAH45620.2,
BAA03515.1,
BAH14788.1
Ensembl_TRS:
ENST00000411637,
ENST00000359428,
ENST00000483497
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000352400,
ENSP00000396576,
ENSP00000436793
RefSeq:
NP_001305253.1,
NP_005076.3,
NP_001305254.1
|
| Others |
UniRef100:
UniRef100_P35658,
UniRef100_B7ZAV2
UniRef90:
UniRef90_P35658,
UniRef90_B7ZAV2
UniRef50:
UniRef50_P35658,
UniRef50_A0A5F5XSF1
UniGene:
Hs.654530
CCDS:
CCDS6940.1,
CCDS83429.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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