| Type | Description |
|---|---|
| Definition | ring finger protein 34 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-28 10:52:00 | Study identified RNF34 as an important regulator of immunity and mitophagy by inducing the autophagic degradation of MAVS aggregates. RNF34 promoted the K63 to K27/K29 ubiquitination transition of MAVS and degraded activated MAVS oligomers. The loss of RNF34 led to defects in mitophagy. The RNF34-mediated mitochondrial quality control mechanism links the innate immune response, mitochondrial homeostasis, and infection. | 31304625 |
| 2015-09-26 20:44:00 | Data indicate that E3 ligase RNF34 is associated with nucleotide-binding oligomerization domain-containing protein 1 (NOD1). | 25012219 |
| 2011-08-06 11:02:00 | Data indicate AE induces caspase-8-mediated activation of mitochondrial death pathways by decreasing the stability of mRNAs in a p53-independent manner. | 21308745 |
| 2010-12-04 11:11:00 | The previously unknown small molecule inhibitor-dependent interaction of Cbeta1 with the cell cycle and apoptosis regulatory protein-1 was verified. | 20564261 |
| 2010-01-21 00:00:00 | together with MDM2 enhance p53 degradation, thereby inhibiting p53-mediated cell death. | 18382127 |
| Type | IDs |
|---|---|
| Synonymous | CARP-1, CARP1, RFI, RIF, RIFF, hRFI |
| Gene |
UniProtKB-ID:
RNF34_HUMAN,
A0A087WTM5_HUMAN
UniprotKB:
Q969K3,
A0A087WTM5
UniParc:
UPI00001FBD24,
UPI000006FBBD,
UPI000006FB34
EMBL:
AY098934,
BC007826,
BT007283,
AF306709,
AB084914,
AK304366,
AK025439,
AC048337,
AC073650,
CR457342
Ensembl:
ENSG00000170633
KO:
hsa:80196
|
| Nucleutide sequences |
EMBL-CDS:
AAK51328.1,
AAH07826.1,
BAB15132.1,
BAH14169.1,
CAG33623.1,
AAM29180.1,
BAC11802.1,
AAP35947.1
Ensembl_TRS:
ENST00000361234,
ENST00000392465,
ENST00000613529
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000376258,
ENSP00000355137,
ENSP00000477987
RefSeq:
XP_024304958.1,
XP_024304959.1,
NP_001243787.1,
NP_919247.1,
NP_079402.2
|
| Others |
UniRef100:
UniRef100_Q969K3,
UniRef100_A0A087WTM5
UniRef90:
UniRef90_Q969K3,
UniRef90_A0A2I3MR74
UniRef50:
UniRef50_Q969K3,
UniRef50_A0A2I3GE82
UniGene:
Hs.292804
CCDS:
CCDS31915.1,
CCDS9221.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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