| Type | Description |
|---|---|
| Definition | MYC target 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 10:22:00 | MYCT1 may synergistically interact with MAX as a co-transcription factor or a component of MAX transcriptional complex, to transcriptionally regulate the expression of miR-181a, which, in turn, decreases NPM1 expression at post-transcriptional levels, leading to enhanced apoptosis in laryngeal cancer cells | 31152622 |
| 2020-03-07 10:45:00 | miR-632 was upregulated and MYCT1 was downregulated in HCC. High miR-632 or low MYCT1 expression was shown as a predictor for poor overall survival of HCC patients. The study also found miR-632 was able to regulate HCC cell growth and invasion through targeting the expression of MYCT1. | 30982352 |
| 2018-03-10 12:18:00 | YY1 promotes proliferation and migration with suppression of apoptosis via directly inhibiting MYCT1 in laryngeal cancer cells, suggesting that YY1 is a useful target as a potential oncogene in laryngeal cancer development and progression. | 28485541 |
| 2017-01-14 11:42:00 | Overexpression of MYCT1, decreased cell viability under serum deprivation and increased tumour cell migration ability. | 26710964 |
| 2016-12-31 10:05:00 | this study has provided the theoretical basis for the further discussion of the effect and mechanism of action of MTLC in the occurrence of laryngeal cancer. | 27072211 |
| Type | IDs |
|---|---|
| Synonymous | MTLC |
| Gene |
UniProtKB-ID:
MYCT1_HUMAN
UniprotKB:
Q8N699
UniParc:
UPI0000073EDB
EMBL:
AL834500,
BC128463,
AF527367,
AL390960,
AK024922,
CH471051,
BC128464,
BC022556
Ensembl:
ENSG00000120279
KO:
hsa:80177
|
| Nucleutide sequences |
EMBL-CDS:
AAH22556.2,
AAM88866.1,
BAB15035.1,
AAI28464.1,
CAD39158.3,
EAW47726.1,
AAI28465.1
Ensembl_TRS:
ENST00000367245
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000356214
RefSeq:
NP_001358555.1,
NP_079383.2,
XP_011534453.1,
NP_001358553.1,
XP_016866808.1,
NP_001358554.1,
XP_011534454.1
|
| Others |
UniRef100:
UniRef100_Q8N699
UniRef90:
UniRef90_Q8N699
UniRef50:
UniRef50_Q8N699
UniGene:
Hs.18160
CCDS:
CCDS5239.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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