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80168 MOGAT2

80168

MOGAT2

monoacylglycerol O-acyltransferase 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition monoacylglycerol O-acyltransferase 2

研究结论

Date Results Publications
2018-06-25 10:42:00 MGAT2 functions as a dimeric or tetrameric protein and selectively heterodimerizes with DGAT1 in mammalian cells 24573674
2018-06-25 10:42:00 MGAT2 is a monoacylglycerol acyltransferase expressed in the small intestine 12621063
2018-06-25 10:41:00 The described cell-based assay adds a new methodology for the development and evaluation of MGAT2 inhibitors for the treatment of obesity and type 2 diabetes 25598079
2018-06-25 10:41:00 Mogat2(IKO) mice increased energy expenditure although to a lesser degree than Mogat2(-/-) mice and were protected against diet-induced weight gain and associated comorbidities 24784138
2018-06-25 10:40:00 Diacylglycerol acyltransferase-2 and monoacylglycerol acyltransferase-2 are ubiquitinated proteins that are degraded by the 26S proteasome 27531967

名称对应

Type IDs
Synonymous DGAT2L5, DGAT2L5., MGAT2, hDC5
Gene
UniProtKB-ID: MOGT2_HUMAN
UniprotKB: Q3SYC2
UniParc: UPI000000D839, UPI0000DD0951, UPI000013C61F
EMBL: BC103878, AY157608, AK026297, AK291998, BC103877, CH471076, BC103876, AK128620
Ensembl: ENSG00000166391
KO: hsa:80168
Nucleutide sequences
EMBL-CDS: AAI03877.1, EAW74983.1, BAB15436.1, AAO23672.1, AAI03878.1, BAC87534.1, BAF84687.1, AAI03879.1
Ensembl_TRS: ENST00000526712, ENST00000198801, ENST00000525093
Protein sequencees
Ensembl_PRO: ENSP00000436283, ENSP00000198801, ENSP00000436537
RefSeq: XP_024304464.1, XP_011543569.1, NP_079374.2
Others
UniRef100: UniRef100_Q3SYC2
UniRef90: UniRef90_Q3SYC2
UniRef50: UniRef50_Q3SYC2
UniGene: Hs.288568
CCDS: CCDS8240.1

全选

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研究热度

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