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80155 NAA15

80155

NAA15

N(alpha)-acetyltransferase 15, NatA auxiliary subunit

protein-coding

Homo sapiens

基因描述

Type Description
Definition N(alpha)-acetyltransferase 15, NatA auxiliary subunit

研究结论

Date Results Publications
2020-05-02 12:21:00 Structure and mechanism of acetylation by the N-terminal dual enzyme NatA/Naa50 complex has been reported. 31155310
2019-06-08 10:43:00 Results provide evidence that Naa15 metazoan-specific domain contributes to N-terminal acetyltransferases A activity and stability. 29754825
2018-12-22 12:01:00 individuals with copy-number variant (CNV) deletions involving NAA15 and surrounding genes can present with mild intellectual disability, mild dysmorphic features, motor delays, and decreased growth. 29656860
2018-11-24 12:04:00 In combination with acetylation assays, the HypK N-terminal region is identified as a negative regulator of the NatA acetylation activity 28585574
2018-08-11 11:46:00 Authors highlight NAA15 as a novel candidate ID gene based on the vital role of NAA15 in the generation and differentiation of neurons in neonatal brain. 28990276

名称对应

Type IDs
Synonymous Ga19, MRD50, NARG1, NAT1P, NATH, TBDN, TBDN100
Gene
UniProtKB-ID: NAA15_HUMAN, B2RBE5_HUMAN, A0A0B4J1W3_HUMAN
UniprotKB: Q9BXJ9, B2RBE5, A0A0B4J1W3
UniParc: UPI000004961C, UPI00017507E6, UPI0000072B59, UPI000004B631
EMBL: BC039818, AC097376, AJ314788, AK023402, AK314626, CH471056, AF327722, BC093928, BC104806, AY112670, AY039242
Ensembl: ENSG00000164134
KO: hsa:80155
Nucleutide sequences
EMBL-CDS: AAM48746.1, AAY40950.1, AAH93928.1, AAK68661.1, CAC43228.1, BAB14562.1, AAH39818.1, AAI04807.1, AAK15707.1, EAX05119.1, BAG37192.1
Ensembl_TRS: ENST00000296543, ENST00000398947
Protein sequencees
Ensembl_PRO: ENSP00000296543, ENSP00000381920
RefSeq: XP_005263293.1, NP_476516.1
Others
UniRef100: UniRef100_A0A0B4J1W3, UniRef100_B2RBE5, UniRef100_Q9BXJ9
UniRef90: UniRef90_Q9BXJ9, UniRef90_H2R9X9
UniRef50: UniRef50_Q9BXJ9, UniRef50_F1N4V5
UniGene: Hs.745047
CCDS: CCDS43270.1

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