| Type | Description |
|---|---|
| Definition | enhancer of mRNA decapping 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-06-01 12:43:00 | EDC3 might be preferentially involved in the degradation of long coding and non-coding RNAs | 29685133 |
| 2016-02-20 11:55:00 | In vitro decapping assays showed that altered EDC3 is unable to enhance DCP2 decapping at low concentrations and even inhibits DCP2 decapping at high concentration. | 25701870 |
| 2010-01-21 00:00:00 | The modular architecture enables EDC3 to interact with multiple components of the decapping machinery, including DCP1, DCP2, and Me31B. | 17923697 |
| 2010-01-21 00:00:00 | Structural basis for the mutually exclusive anchoring of P body components EDC3 and Tral to the DEAD box protein DDX6/Me31B. | 19285948 |
| 2010-01-21 00:00:00 | The dimerization interface of Edc3 is highly conserved in eukaryotes despite the overall low sequence homology across species; structure-based site-directed mutagenesis revealed dimerization is required for efficient RNA binding, P-body formation | 18678652 |
| Type | IDs |
|---|---|
| Synonymous | LSM16, MRT50, YJDC, YJEFN2, hYjeF_N2-15q23 |
| Gene |
UniProtKB-ID:
EDC3_HUMAN
UniprotKB:
Q96F86
UniParc:
UPI000007309A
EMBL:
AF193058,
AK056339,
BC021271,
AK024781,
CH471136,
BC011534
Ensembl:
ENSG00000179151
KO:
hsa:80153
|
| Nucleutide sequences |
EMBL-CDS:
AAG22486.1,
EAW99317.1,
BAB15001.1,
AAH21271.1,
BAG51682.1,
EAW99316.1,
EAW99319.1,
EAW99318.1,
AAH11534.1
Gene_ORFName:
PP844
Ensembl_TRS:
ENST00000647659,
ENST00000315127,
ENST00000426797,
ENST00000568176
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000320503,
ENSP00000455580,
ENSP00000497737,
ENSP00000401343
RefSeq:
NP_001135916.1,
XP_024305846.1,
XP_011520394.1,
NP_001338308.1,
XP_024305845.1,
XP_024305847.1,
NP_001135915.1,
NP_001338307.1,
NP_079359.2
|
| Others |
UniRef100:
UniRef100_Q96F86
UniRef90:
UniRef90_Q96F86
UniRef50:
UniRef50_Q96F86
UniGene:
Hs.96852,
Hs.682454
CCDS:
CCDS10267.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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