| Type | Description |
|---|---|
| Definition | centromere protein T |
| Date | Results | Publications |
|---|---|---|
| 2019-04-20 10:58:00 | these data define a novel molecular mechanism underlying the assembly of CENP-T onto the centromere by a temporally regulated HJURP-CENP-T interaction. | 30459232 |
| 2018-04-14 10:03:00 | Levels of centromere aberrations increase upon depletion of CENP-A, CENP-C, and CENP-T/W, during replicative senescence, and in cancer cells. | 28167779 |
| 2018-01-06 11:57:00 | report a novel disease gene encoding the constitutive inner kinetochore member CENPT, which is involved in kinetochore targeting and assembly, resulting in severe growth failure in two siblings of a consanguineous family | 29228025 |
| 2018-01-06 10:44:00 | Upon cross-linking, the entire CENPA/CENPB/CENPC/CENPT complex is nuclease-protected over an alpha-satellite dimer that comprises the fundamental unit of centromeric chromatin. We conclude that CENPA/CENPC and CENPT pathways for kinetochore assembly are physically integrated over young alpha-satellite dimers. | 27384170 |
| 2017-10-28 11:55:00 | Whereas CENP-C recruits a single MIS12:NDC80 complex, the authors show here that CENP-T binds one MIS12:NDC80 and two NDC80 complexes upon phosphorylation by the mitotic CDK1:Cyclin B complex at three distinct CENP-T sites. | 28012276 |
| Type | IDs |
|---|---|
| Synonymous | C16orf56, CENP-T |
| Gene |
UniProtKB-ID:
CENPT_HUMAN,
B3KPB2_HUMAN
UniprotKB:
Q96BT3,
B3KPB2
UniParc:
UPI0000070555,
UPI000006E085,
UPI00001A82D9,
UPI00001C1CDE
EMBL:
AK056097,
BC007864,
AK055237,
BC015202,
BC007642,
AK023173
Ensembl:
ENSG00000102901
KO:
hsa:80152
|
| Nucleutide sequences |
EMBL-CDS:
AAH07642.1,
BAB14445.1,
AAH15202.2,
AAH07864.2,
BAB70884.1,
BAG51624.1
Ensembl_TRS:
ENST00000562787,
ENST00000440851
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000400140,
ENSP00000457810
RefSeq:
XP_024306223.1,
XP_024306224.1,
NP_079358.3,
XP_011521647.1,
XP_016879204.1,
XP_024306225.1,
XP_024306226.1,
XP_016879206.1
|
| Others |
UniRef100:
UniRef100_Q96BT3,
UniRef100_B3KPB2
UniRef90:
UniRef90_Q96BT3
UniRef50:
UniRef50_Q96BT3
UniGene:
Hs.288382
CCDS:
CCDS42182.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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