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80143 SIKE1

80143

SIKE1

suppressor of IKBKE 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition suppressor of IKBKE 1

研究结论

Date Results Publications
2019-08-03 11:24:00 mRNA expression of individual inhibitory kappaB kinases and SIKE are associated with unique prognostic significance and may act as valuable prognostic biomarkers and potential targets for future therapeutic interventions in gastric cancer. 30487159
2018-07-28 11:13:00 SIKE, a negative regulator of the interferon pathway, attenuates pathological cardiac hypertrophy. 27249321
2013-09-07 11:56:00 Data indicate that suppressor of IKKepsilon (SIKE) inhibits TANK-binding kinase 1 (TBK1)-mediated phosphorylation of interferon regulatory factor 3 (IRF3), which is essential to type I interferon production. 23649622
2010-01-21 00:00:00 Overexpression of SIKE inhibits virus- and Toll-like receptor 3-triggered interferon-stimulated response elements (ISRE) but not NF-kappa B activation. 16281057

名称对应

Type IDs
Synonymous SIKE
Gene
UniProtKB-ID: SIKE1_HUMAN
UniprotKB: Q9BRV8
UniParc: UPI00000703B7, UPI0000470A25
EMBL: CR749219, CH471122, BC005934, AK024821, AL096773
Ensembl: ENSG00000052723
KO: hsa:80143
Nucleutide sequences
EMBL-CDS: EAW56620.1, BAB15020.1, CAH18076.1, AAH05934.1
Ensembl_TRS: ENST00000060969, ENST00000369528
Protein sequencees
Ensembl_PRO: ENSP00000358541, ENSP00000060969
RefSeq: NP_001095866.1, NP_079349.2
Others
UniRef100: UniRef100_Q9BRV8
UniRef90: UniRef90_Q9BRV8
UniRef50: UniRef50_Q9BRV8
UniGene: Hs.709277
CCDS: CCDS41371.1, CCDS878.1

全选

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研究热度

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