| Type | Description |
|---|---|
| Definition | coiled-coil domain containing 170 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:55:00 | Therapeutic role of recurrent ESR1-CCDC170 gene fusions in breast cancer endocrine resistance. | 32771039 |
| 2020-04-18 10:46:00 | The study shows that an association of theRMND1/CCDC170-ESR1 single nucleotide polymorphisms can exist with osteopenia, osteoporosis, or fragility fracture. | 30601066 |
| 2018-02-03 10:22:00 | Findings demonstrate that CCDC170 plays an essential role in Golgi-associated microtubules organization and stabilization, and implicate a mechanism for how perturbations in the CCDC170 gene may contribute to the hallmark changes in cell polarity and motility seen in breast cancer. | 28687497 |
| 2016-10-01 10:10:00 | Genetic variation at the WLS and CCDC170/ESR1 loci were found to be significantly associated with bone mineral density | 26911590 |
| 2016-08-13 10:16:00 | Expression of ESR1, RMND1 and CCDC170 associated with variants in separate enhancer elements predisposing breast cancer. [meta-analysis] | 26928228 |
| Type | IDs |
|---|---|
| Synonymous | C6orf97, bA282P11.1 |
| Gene |
UniProtKB-ID:
CC170_HUMAN
UniprotKB:
Q8IYT3
UniParc:
UPI000020D0BA
EMBL:
AL590543,
AL359494,
AK027300,
AK026958,
BC060803
Ensembl:
ENSG00000120262
KO:
hsa:80129
|
| Nucleutide sequences |
EMBL-CDS:
BAB55025.1,
BAB15602.1,
AAH60803.1
Ensembl_TRS:
ENST00000239374
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000239374
RefSeq:
NP_079335.2,
XP_011534450.1,
XP_011534449.1
|
| Others |
UniRef100:
UniRef100_Q8IYT3
UniRef90:
UniRef90_Q8IYT3
UniRef50:
UniRef50_Q8IYT3
UniGene:
Hs.660044
CCDS:
CCDS43515.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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