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80124 VCPIP1

80124

VCPIP1

valosin containing protein interacting protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition valosin containing protein interacting protein 1

研究结论

Date Results Publications
2018-05-12 10:50:00 BoNT/A catalytic light chain binds to, and is a substrate for, the ubiquitin ligase HECTD2. However, the light chain evades proteasomal degradation by the dominant effect of a deubiquitinating enzyme, VCIP135/VCPIP1. This deubiquitinating enzyme binds BoNT/A light chain directly. 28584101
2016-05-21 12:45:00 Phosphorylation and ubiquitination are coordinated via VCIP135 to control Golgi membrane dynamics in the cell cycle. 25904330
2014-08-23 10:05:00 VCIP135 phosphorylation regulates its Golgi membrane association and p97 interaction, and thus contributes to the tight control of the Golgi disassembly and reassembly process during the cell cycle. 24163436
2013-06-08 12:21:00 the phosphorylation of VCIP135 on Threonine-760 and Serine-767 inhibits p97-mediated Golgi membrane fusion at mitosis 23500464
2010-01-21 00:00:00 evidence of tyrosine phosphorylation during sperm capacitation 12509440

名称对应

Type IDs
Synonymous DUBA3, VCIP135
Gene
UniProtKB-ID: VCIP1_HUMAN
UniprotKB: Q96JH7
UniParc: UPI00001D3EF3
EMBL: AB058753, AL832606, AK026785, AL834476, BC094799, BC049379
Ensembl: ENSG00000175073
KO: hsa:80124
Nucleutide sequences
EMBL-CDS: CAD89944.1, AAH94799.1, BAB47479.1, AAH49379.1, CAD39135.1, BAB15552.1
Ensembl_TRS: ENST00000310421
Protein sequencees
Ensembl_PRO: ENSP00000309031
RefSeq: NP_079330.2
Others
UniRef100: UniRef100_Q96JH7
UniRef90: UniRef90_Q96JH7
UniRef50: UniRef50_Q96JH7
UniGene: Hs.632066
CCDS: CCDS6192.1

全选

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