Type | Description |
---|---|
Definition | mitogen-activated protein kinase kinase kinase 19 |
Date | Results | Publications |
---|---|---|
2021-01-09 13:28:00 | The protein kinase MAP3K19 phosphorylates MAP2Ks and thereby activates ERK and JNK kinases and increases viability of KRAS-mutant lung cancer cells. | 32358059 |
2017-07-29 11:24:00 | Mitogen-activated protein kinase kinase kinase 19 (MAP3K19) is overexpressed in the lungs of chronic obstructive pulmonary disease (COPD) patients. | 27935962 |
Type | IDs |
---|---|
Synonymous | RCK, YSK4 |
Gene |
UniProtKB-ID:
M3K19_HUMAN
UniprotKB:
Q56UN5
UniParc:
UPI00004F77F3,
UPI00004F77F5,
UPI00004F77F6,
UPI00004F77F2,
UPI0001917067
EMBL:
AY574903,
AK026727,
AC016725,
BC137277,
AC020602,
BC144555,
AY574902,
AY574904,
BC034417,
AY574901,
AY574905,
BC137276
Ensembl:
ENSG00000176601
KO:
hsa:80122
|
Nucleutide sequences |
EMBL-CDS:
AAT81411.1,
AAT81414.1,
AAT81413.1,
AAY14999.1,
AAI44556.1,
BAB15538.1,
AAI37278.1,
AAI37277.1,
AAT81412.1,
AAH34417.1,
AAT81410.1
Ensembl_TRS:
ENST00000358371,
ENST00000392917,
ENST00000392915,
ENST00000375844,
ENST00000375845,
ENST00000392918
|
Protein sequencees |
Ensembl_PRO:
ENSP00000365005,
ENSP00000351140,
ENSP00000376647,
ENSP00000376649,
ENSP00000376650,
ENSP00000365004
RefSeq:
XP_016860495.1,
NP_079328.3,
NP_001269812.1,
XP_016860494.1,
NP_001018057.1,
XP_011510198.1,
XP_011510199.1,
XP_011510196.1,
NP_001308106.1,
NP_001018056.1,
XP_016860496.1,
NP_001018054.1,
XP_011510193.1,
XP_016860493.1,
XP_011510194.1
|
Others |
UniRef100:
UniRef100_Q56UN5
UniRef90:
UniRef90_Q56UN5
UniRef50:
UniRef50_Q56UN5
UniGene:
Hs.659395
CCDS:
CCDS63020.1,
CCDS2176.2,
CCDS63021.1,
CCDS63022.1,
CCDS33293.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
32358059 |
J Biol Chem Van T Hoang , Katherine Nyswaner , Pedro Torres-Ayuso , John Brognard |
2020-06-19 | - |
31478661 |
J. Proteome Res. Luiz E Silva , Renan C Souza , Eduardo S Kitano , Lucas F Monteiro , Leo K Iwai , Fabio L Forti |
2019-10-04 | - |
27144281 |
PLoS ONE Stefen A Boehme , Karin Franz-Bacon , Danielle N DiTirro , Tai Wei Ly , Kevin B Bacon |
2016-01-01 | - |
27935962 |
PLoS ONE Stefen A Boehme , Karin Franz-Bacon , John Ludka , Danielle N DiTirro , Tai Wei Ly , Kevin B Bacon |
2016-01-01 | - |
24705354 |
Hum. Mol. Genet. Stefanie L Butland , Shaun S Sanders , Mandi E Schmidt , Sean-Patrick Riechers , David T S Lin , Dale D O Martin , Kuljeet Vaid , Rona K Graham , Roshni R Singaraja , Erich E Wanker , Elizabeth Conibear , Michael R Hayden |
2014-08-01 | - |
21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
15815621 |
Generation and annotation of the DNA sequences of human chromosomes 2 and 4. Nature Ladeana W Hillier , Tina A Graves , Robert S Fulton , Lucinda A Fulton , Kymberlie H Pepin , Patrick Minx , Caryn Wagner-McPherson , Dan Layman , Kristine Wylie , Mandeep Sekhon , Michael C Becker , Ginger A Fewell , Kimberly D Delehaunty , Tracie L Miner , William E Nash , Colin Kremitzki , Lachlan Oddy , Hui Du , Hui Sun , Holland Bradshaw-Cordum , Johar Ali , Jason Carter , Matt Cordes , Anthony Harris , Amber Isak , Andrew van Brunt , Christine Nguyen , Feiyu Du , Laura Courtney , Joelle Kalicki , Philip Ozersky , Scott Abbott , Jon Armstrong , Edward A Belter , Lauren Caruso , Maria Cedroni , Marc Cotton , Teresa Davidson , Anu Desai , Glendoria Elliott , Thomas Erb , Catrina Fronick , Tony Gaige , William Haakenson , Krista Haglund , Andrea Holmes , Richard Harkins , Kyung Kim , Scott S Kruchowski , Cynthia Madsen Strong , Neenu Grewal , Ernest Goyea , Shunfang Hou , Andrew Levy , Scott Martinka , Kelly Mead , Michael D McLellan , Rick Meyer , Jennifer Randall-Maher , Chad Tomlinson , Sara Dauphin-Kohlberg , Amy Kozlowicz-Reilly , Neha Shah , Sharhonda Swearengen-Shahid , Jacqueline Snider , Joseph T Strong , Johanna Thompson , Martin Yoakum , Shawn Leonard , Charlene Pearman , Lee Trani , Maxim Radionenko , Jason E Waligorski , Chunyan Wang , Susan M Rock , Aye-Mon Tin-Wollam , Rachel Maupin , Phil Latreille , Michael C Wendl , Shiaw-Pyng Yang , Craig Pohl , John W Wallis , John Spieth , Tamberlyn A Bieri , Nicolas Berkowicz , Joanne O Nelson , John Osborne , Li Ding , Rekha Meyer , Aniko Sabo , Yoram Shotland , Prashant Sinha , Patricia E Wohldmann , Lisa L Cook , Matthew T Hickenbotham , James Eldred , Donald Williams , Thomas A Jones , Xinwei She , Francesca D Ciccarelli , Elisa Izaurralde , James Taylor , Jeremy Schmutz , Richard M Myers , David R Cox , Xiaoqiu Huang , John D McPherson , Elaine R Mardis , Sandra W Clifton , Wesley C Warren , Asif T Chinwalla , Sean R Eddy , Marco A Marra , Ivan Ovcharenko , Terrence S Furey , Webb Miller , Evan E Eichler , Peer Bork , Mikita Suyama , David Torrents , Robert H Waterston , Richard K Wilson |
2005-04-07 |
NEMP2,
SP9,
GKN3P,
CLDN24,
LOC100133128,
ARHGEF33,
LIMS4,
DUX4L9,
ACTR1B,
USP17L23,
CEBPZ,
TXNDC9,
STAM2,
SPEG,
NMUR1,
UBE2E3,
STK25,
SEMA4F,
CCT7,
CCT4,
CENPA,
CDC42EP3,
MXD4,
STAMBP,
TBR1,
MAP3K2,
MTHFD2,
PROKR1,
PPBPP2,
ADCY3,
GPR75,
SNRNP27,
RABL2A,
CHN1,
GPR45,
CFAP36,
CHRND,
CHRNG,
GALNT13,
DIRC1,
MOGAT1,
ARAP2,
ADD1,
ADD2,
CNGA3,
COL3A1,
COL4A3,
COL5A2,
TMEM150A,
NUP35,
MITD1,
NEU4,
UBTFL3,
BBS5,
ICA1L,
REG3G,
RFTN2,
ACVR1C,
OSR1,
UBR3,
KCTD18,
CPO,
PQLC3,
TMEM155,
PACRGL,
COX7A2P2,
MYO3B,
UBE2F,
CRYGB,
CRYGD,
DUSP19,
CTLA4,
CTNNA2,
TEKT4,
C2orf15,
OTOS,
FBXO41,
SEPT10,
ADRA2B,
SGO2,
ALS2CR11,
FAM84A,
ASPRV1,
WDSUB1,
UPP2,
GPR155,
NFXL1,
MGAT4D,
PPM1K,
TRMT44,
DBI,
DAW1,
OXER1,
FREM3,
TIGD2,
AGA,
DOK1,
E2F6,
EEF1B2
|
15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
14702039 |
Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat. Genet. Toshio Ota , Yutaka Suzuki , Tetsuo Nishikawa , Tetsuji Otsuki , Tomoyasu Sugiyama , Ryotaro Irie , Ai Wakamatsu , Koji Hayashi , Hiroyuki Sato , Keiichi Nagai , Kouichi Kimura , Hiroshi Makita , Mitsuo Sekine , Masaya Obayashi , Tatsunari Nishi , Toshikazu Shibahara , Toshihiro Tanaka , Shizuko Ishii , Jun-ichi Yamamoto , Kaoru Saito , Yuri Kawai , Yuko Isono , Yoshitaka Nakamura , Kenji Nagahari , Katsuhiko Murakami , Tomohiro Yasuda , Takao Iwayanagi , Masako Wagatsuma , Akiko Shiratori , Hiroaki Sudo , Takehiko Hosoiri , Yoshiko Kaku , Hiroyo Kodaira , Hiroshi Kondo , Masanori Sugawara , Makiko Takahashi , Katsuhiro Kanda , Takahide Yokoi , Takako Furuya , Emiko Kikkawa , Yuhi Omura , Kumi Abe , Kumiko Kamihara , Naoko Katsuta , Kazuomi Sato , Machiko Tanikawa , Makoto Yamazaki , Ken Ninomiya , Tadashi Ishibashi , Hiromichi Yamashita , Katsuji Murakawa , Kiyoshi Fujimori , Hiroyuki Tanai , Manabu Kimata , Motoji Watanabe , Susumu Hiraoka , Yoshiyuki Chiba , Shinichi Ishida , Yukio Ono , Sumiyo Takiguchi , Susumu Watanabe , Makoto Yosida , Tomoko Hotuta , Junko Kusano , Keiichi Kanehori , Asako Takahashi-Fujii , Hiroto Hara , Tomo-o Tanase , Yoshiko Nomura , Sakae Togiya , Fukuyo Komai , Reiko Hara , Kazuha Takeuchi , Miho Arita , Nobuyuki Imose , Kaoru Musashino , Hisatsugu Yuuki , Atsushi Oshima , Naokazu Sasaki , Satoshi Aotsuka , Yoko Yoshikawa , Hiroshi Matsunawa , Tatsuo Ichihara , Namiko Shiohata , Sanae Sano , Shogo Moriya , Hiroko Momiyama , Noriko Satoh , Sachiko Takami , Yuko Terashima , Osamu Suzuki , Satoshi Nakagawa , Akihiro Senoh , Hiroshi Mizoguchi , Yoshihiro Goto , Fumio Shimizu , Hirokazu Wakebe , Haretsugu Hishigaki , Takeshi Watanabe , Akio Sugiyama , Makoto Takemoto , Bunsei Kawakami , Masaaki Yamazaki , Koji Watanabe , Ayako Kumagai , Shoko Itakura , Yasuhito Fukuzumi , Yoshifumi Fujimori , Megumi Komiyama , Hiroyuki Tashiro , Akira Tanigami , Tsutomu Fujiwara , Toshihide Ono , Katsue Yamada , Yuka Fujii , Kouichi Ozaki , Maasa Hirao , Yoshihiro Ohmori , Ayako Kawabata , Takeshi Hikiji , Naoko Kobatake , Hiromi Inagaki , Yasuko Ikema , Sachiko Okamoto , Rie Okitani , Takuma Kawakami , Saori Noguchi , Tomoko Itoh , Keiko Shigeta , Tadashi Senba , Kyoka Matsumura , Yoshie Nakajima , Takae Mizuno , Misato Morinaga , Masahide Sasaki , Takushi Togashi , Masaaki Oyama , Hiroko Hata , Manabu Watanabe , Takami Komatsu , Junko Mizushima-Sugano , Tadashi Satoh , Yuko Shirai , Yukiko Takahashi , Kiyomi Nakagawa , Koji Okumura , Takahiro Nagase , Nobuo Nomura , Hisashi Kikuchi , Yasuhiko Masuho , Riu Yamashita , Kenta Nakai , Tetsushi Yada , Yusuke Nakamura , Osamu Ohara , Takao Isogai , Sumio Sugano |
2004-01-01 |
Slc9a8,
Nefm,
Hfe2,
AKT3,
ZBTB11-AS1,
LOC100034248,
PDZK1P1,
DDTL,
LOC100049716,
ACOT8,
GNPDA1,
ZBTB33,
GTF2IP4,
POM121C,
ZSCAN30,
SRA1,
SNORD123,
UCKL1-AS1,
ZGLP1,
LOC100125918,
LINC00322,
LOC100127940,
HECW1-IT1,
LOC100127955,
LOC100127972,
LOC100127974,
FAM229A,
LOC100128076,
STAU2-AS1,
LOC100128164,
TMPO-AS1,
LOC100128219,
LOC100128239,
LOC100128253,
TNK2-AS1,
DNM1P35,
LOC100128288,
DLG5-AS1,
LOC100128310,
TRAPPC3L,
FAM83H-AS1,
LOC100128361,
LOC100128364,
FAM225B,
LOC100128386,
LOC100128398,
ASTN2-AS1,
C1orf132,
MYHAS,
LOC100128651,
LINC00476,
SRRM2-AS1,
GPR158-AS1,
LINC01165,
VPS9D1-AS1,
FAM66B,
GATA6-AS1,
LINC01310,
LOC100128979,
LOC100128988,
LOC100129034,
SEMA3F-AS1,
UNQ6494,
LOC100129115,
KHDC1L,
LOC100129175,
MATN1-AS1,
SLC39A12-AS1,
LOC100129297,
LOC100129312,
LINC00484,
LOC100129397,
LOC100129406,
DDC-AS1,
LOC100129434,
LOC100129447,
LOC100129455,
LYRM4-AS1,
ZNF37BP,
LOC100129516,
LOC100129518,
LOC100129540,
LOC100129572,
FAM47E,
LOC100129620,
LOC100129648,
C9orf173-AS1,
LOC100129775,
SLC25A21-AS1,
PCOLCE-AS1,
SCOC-AS1,
LOC100129884,
LOC100129894,
LOC100129917,
LOC100129935,
LOC100130078,
LOC100130111,
MAPT-IT1,
MIR124-2HG
|
12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
排名 | 科研单位 | 文献 |
---|---|---|
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排名 | 研究人员 | 文献 |
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目前还没有研究热点人员