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80004 ESRP2

80004

ESRP2

epithelial splicing regulatory protein 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition epithelial splicing regulatory protein 2

研究结论

Date Results Publications
2021-01-02 12:48:00 Epithelial splicing regulatory protein 2-mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis. 31945016
2020-02-22 10:57:00 Here the authors find androgens regulate splicing through androgen receptor-mediated transcriptional control of the epithelial-specific splicing regulator ESRP2. Androgen stimulation induces splicing switches in many endogenous ESRP2-controlled mRNA isoforms, including splicing switches correlating with disease progression. 31478829
2018-12-22 10:44:00 In conclusion, our findings suggested that IFNG-AS1 may function as an oncogene in pituitary adenoma by interacting with ESRP2. 30322807
2018-02-24 11:06:00 Results showed that the expression patterns of these genes were indicative of the onset of EMT in in-vitro models, but not in tissue samples. However, the ratio between ESRP1 or ESRP2 and RBFOX2 significantly decreased during EMT and positively correlated with the EMT-specific phenotype in cell models. Low ESRP1/RBFOX2 ratio value was associated with a higher risk of metastasis in early breast cancer patients. 27911856
2017-09-16 10:05:00 Results indicate a tumor-suppressive role of the ring finger protein 111 (Arkadia)-epithelial splicing regulatory protein 2 (ESRP2) axis in clear-cell renal cell carcinoma (ccRCC). 26522722

名称对应

Type IDs
Synonymous RBM35B
Gene
UniProtKB-ID: ESRP2_HUMAN
UniprotKB: Q9H6T0
UniParc: UPI0000070326, UPI000006FB08
EMBL: BC030146, AK025901, AK025571, AF289577
Ensembl: ENSG00000103067
KO: hsa:80004
Nucleutide sequences
EMBL-CDS: AAL55761.1, BAB15173.1, AAH30146.1, BAB15275.1
Gene_ORFName: PP7059
Ensembl_TRS: ENST00000565858, ENST00000473183
Protein sequencees
Ensembl_PRO: ENSP00000454554, ENSP00000418748
RefSeq: NP_001352194.1, NP_001352193.1, NP_079215.2, XP_005256210.1, XP_006721336.1
Others
UniRef100: UniRef100_Q9H6T0
UniRef90: UniRef90_Q9H6T0
UniRef50: UniRef50_Q9H6T0
UniGene: Hs.436585, Hs.592053
CCDS: CCDS10863.1

全选

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