| Type | Description |
|---|---|
| Definition | STN1 subunit of CST complex |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 11:55:00 | The study investigated whether six genetic variants previously associated with leukocyte telomere length are correlated with telomere length in peripheral blood mononuclear cells in a cohort of Africans living with and without HIV and undergoing evaluation for tuberculosis (TB). OBFC1 and the genetic sum score of the effect alleles across all six loci were found to be associated with shorter telomere length. | 31388112 |
| 2020-02-29 11:22:00 | CST functions in two distinct aspects of genome-wide DNA replication, namely, origin licensing and replisome assembly. CST interacts with additional replisome components, MCM and AND-1. | 30979824 |
| 2019-12-07 11:33:00 | The CST complex (CTC1-STN1-TEN1) maintains genome integrity through resolution of G4 structures both ahead of the replication fork and on the lagging strand template | 30976812 |
| 2019-11-30 12:15:00 | Association of OBFC1 gene single nucleotide polymorphisms with laryngeal carcinoma in Chinese Han male population. | 31016429 |
| 2019-10-12 10:52:00 | Impaired interaction between CTC1(L1142H) :STN1 and DNA Pol-alpha results in increased telomerase recruitment to telomeres and further telomere elongation, revealing that C:S binding to DNA Pol-alpha is required to fully repress telomerase activity. | 29774655 |
| Type | IDs |
|---|---|
| Synonymous | AAF-44, AAF44, OBFC1, RPA-32, bA541N10.2 |
| Gene |
UniProtKB-ID:
STN1_HUMAN
UniprotKB:
Q9H668
UniParc:
UPI000013C85A
EMBL:
BC017400,
CH471066,
AK026212,
AL133355
Ensembl:
ENSG00000107960
KO:
hsa:79991
|
| Nucleutide sequences |
EMBL-CDS:
EAW49620.1,
AAH17400.1,
EAW49619.1,
BAB15396.1
Ensembl_TRS:
ENST00000369764,
ENST00000224950
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000224950,
ENSP00000358779
RefSeq:
NP_079204.2
|
| Others |
UniRef100:
UniRef100_Q9H668
UniRef90:
UniRef90_Q9H668
UniRef50:
UniRef50_Q9H668
UniGene:
Hs.62314
CCDS:
CCDS7552.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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