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79969 ATAT1

79969

ATAT1

alpha tubulin acetyltransferase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition alpha tubulin acetyltransferase 1

研究结论

Date Results Publications
2020-01-11 10:39:00 The interactions of GCN5L1, RanBP2 and alphaTAT1 function in concert to control alpha-tubulin acetylation and may contribute towards the regulation of cellular lysosome positioning. 30333138
2019-02-23 12:46:00 the actin-MRTF-SRF circuit controls alpha-TAT1 transcription. INF2 regulates the circuit, and hence microtubule acetylation, in cell types where it has a prominent role in actin polymerization. 29321169
2019-01-19 12:32:00 The specific distributions of ATAT1 through the cell cycle in fibroblasts suggest multiple functions of ATAT1, which could include acetylation of microtubules, RNA transcription activity, severing microtubules, and completion of cytokinesis. 29869029
2018-05-26 11:29:00 these results demonstrate alphaTAT1 enters the lumen of microtubules from open extremities and spreads K40 acetylation marks longitudinally along cellular microtubules; this mode of tip-directed microtubule acetylation may allow for selective acetylation of subsets of microtubules 27752143
2017-12-02 12:19:00 Depletion of the tubulin acetyltransferase TAT1 led to a significant increase in the frequency of microtubule breakage. 28428427

名称对应

Type IDs
Synonymous C6orf134, MEC17, Nbla00487, TAT, alpha-TAT, alpha-TAT1
Gene
UniProtKB-ID: ATAT_HUMAN, A0A1U9X797_HUMAN, B7Z4Q7_HUMAN
UniprotKB: Q5SQI0, A0A1U9X797, B7Z4Q7
UniParc: UPI000014137B, UPI00001AF231, UPI0000070EA8, UPI0000E5ACC6, UPI000006CF3A, UPI00001AE9CB, UPI000000DBC9, UPI0001914F5B
EMBL: KY500156, KY500155, AK297661, CR753328, AB075512, BX908728, AL732442, BX119957, CH471081, AL845353, CR759778, AK023220, BC006105, BC047303, AL662800, AL833858
Ensembl: ENSG00000137343, ENSG00000229061, ENSG00000223752, ENSG00000231257, ENSG00000235658, ENSG00000234549, ENSG00000206488
KO: hsa:79969
Nucleutide sequences
EMBL-CDS: BAB14472.1, AAH47303.1, AAH06105.1, BAE45758.1, CAD38717.1, EAX03306.1, EAX03307.1, AQY76660.1, AQY76659.1, BAH12643.1
Gene_ORFName: Nbla00487
Ensembl_TRS: ENST00000400576, ENST00000424121, ENST00000457334, ENST00000400575, ENST00000425448, ENST00000383585, ENST00000448670, ENST00000428764, ENST00000383582, ENST00000416435, ENST00000446100, ENST00000383584, ENST00000376483, ENST00000432643, ENST00000443391, ENST00000457161, ENST00000454794, ENST00000456704, ENST00000423654, ENST00000376485, ENST00000417183, ENST00000418248, ENST00000449905, ENST00000443114, ENST00000442844, ENST00000329992, ENST00000416917, ENST00000420586, ENST00000430611, ENST00000319027, ENST00000383583, ENST00000445486, ENST00000454987, ENST00000456215, ENST00000445973, ENST00000450003, ENST00000330083, ENST00000411724, ENST00000318999, ENST00000423338, ENST00000450220, ENST00000432356
Protein sequencees
Ensembl_PRO: ENSP00000393868, ENSP00000411050, ENSP00000389129, ENSP00000373079, ENSP00000383419, ENSP00000406071, ENSP00000324459, ENSP00000327832, ENSP00000416925, ENSP00000394914, ENSP00000383420, ENSP00000399509, ENSP00000399452, ENSP00000388617, ENSP00000402998, ENSP00000398374, ENSP00000406421, ENSP00000412993, ENSP00000398422, ENSP00000388171, ENSP00000399529, ENSP00000373077, ENSP00000394357, ENSP00000391244, ENSP00000409067, ENSP00000411362, ENSP00000365666, ENSP00000415408, ENSP00000415000, ENSP00000373078, ENSP00000412198, ENSP00000403142, ENSP00000405656, ENSP00000410415, ENSP00000405036, ENSP00000373076, ENSP00000365668, ENSP00000332374, ENSP00000416994, ENSP00000324222, ENSP00000409296, ENSP00000393269
RefSeq: NP_001241881.1, NP_001026892.1, NP_079185.2, NP_001177653.1, NP_001305692.1, NP_001305691.1
Others
UniRef100: UniRef100_B7Z4Q7, UniRef100_Q5SQI0, UniRef100_A0A1U9X797
UniRef90: UniRef90_B7Z4Q7, UniRef90_Q5SQI0
UniRef50: UniRef50_Q5SQI0
UniGene: Hs.654798
CCDS: CCDS83073.1, CCDS4683.2, CCDS59002.1, CCDS54978.1, CCDS83072.1

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