| Type | Description |
|---|---|
| Definition | centrosomal protein 76 |
| Date | Results | Publications |
|---|---|---|
| 2017-09-02 12:36:00 | Here, we found that centrosomal protein of 76 kDa (Cep76), previously shown to restrain centriole amplification, interacts with cyclin-dependent kinase 2 (CDK2) and is a bona fide substrate of this kinase. Cep76 is preferentially phosphorylated by cyclin A/CDK2 at a single site S83, and this event is crucial to suppress centriole amplification in S phase | 27065328 |
| 2010-01-21 00:00:00 | Enforced Cep76 expression specifically inhibits centriole amplification in cells undergoing multiple rounds of duplication without preventing the formation of extra procentrioles from a parental template. | 19460342 |
| Type | IDs |
|---|---|
| Synonymous | C18orf9, HsT1705 |
| Gene |
UniProtKB-ID:
CEP76_HUMAN,
B4DP81_HUMAN
UniprotKB:
Q8TAP6,
B4DP81
UniParc:
UPI00000715E7,
UPI00017A7818,
UPI0001A61537,
UPI00017A812D
EMBL:
AK022604,
AP005482,
CH471113,
EF445040,
AL833727,
AK303117,
BC026307,
AK298223,
AK301964
Ensembl:
ENSG00000101624
KO:
hsa:79959
|
| Nucleutide sequences |
EMBL-CDS:
BAG63377.1,
CAH56252.1,
BAG64223.1,
EAX01543.1,
ACA06091.1,
AAH26307.1,
BAB14123.1,
BAG60493.1
Ensembl_TRS:
ENST00000262127,
ENST00000423709,
ENST00000587929
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000262127,
ENSP00000403074,
ENSP00000466833
RefSeq:
XP_016881474.1,
XP_016881472.1,
XP_016881471.1,
XP_016881476.1,
XP_016881475.1,
NP_001258918.1,
NP_079175.2,
XP_016881473.1,
XP_016881470.1,
XP_005258206.1
|
| Others |
UniRef100:
UniRef100_Q8TAP6,
UniRef100_B4DP81
UniRef90:
UniRef90_B4DP81,
UniRef90_Q8TAP6
UniRef50:
UniRef50_Q8TAP6,
UniRef50_B4DP81
UniGene:
Hs.236940
CCDS:
CCDS62390.1,
CCDS11861.1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| 1 |
Dana-Farber Cancer Institute |
8 |
| 2 |
University of Toronto |
7 |
| 3 |
McGill University |
6 |
| 4 |
Lunenfeld-Tanenbaum Research Institute |
5 |
| 5 |
Institute for Research in Biomedicine (IRB Barcelona) |
4 |
| 排名 | 研究人员 | 文献 |
|---|---|---|
| 1 |
David E Hill |
9 |
| 2 |
Marc Vidal |
9 |
| 3 |
Tong Hao |
9 |
| 4 |
Frederick P Roth |
8 |
| 5 |
Xinping Yang |
7 |