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79959 CEP76

79959

CEP76

centrosomal protein 76

protein-coding

Homo sapiens

基因描述

Type Description
Definition centrosomal protein 76

研究结论

Date Results Publications
2017-09-02 12:36:00 Here, we found that centrosomal protein of 76 kDa (Cep76), previously shown to restrain centriole amplification, interacts with cyclin-dependent kinase 2 (CDK2) and is a bona fide substrate of this kinase. Cep76 is preferentially phosphorylated by cyclin A/CDK2 at a single site S83, and this event is crucial to suppress centriole amplification in S phase 27065328
2010-01-21 00:00:00 Enforced Cep76 expression specifically inhibits centriole amplification in cells undergoing multiple rounds of duplication without preventing the formation of extra procentrioles from a parental template. 19460342

名称对应

Type IDs
Synonymous C18orf9, HsT1705
Gene
UniProtKB-ID: CEP76_HUMAN, B4DP81_HUMAN
UniprotKB: Q8TAP6, B4DP81
UniParc: UPI00000715E7, UPI00017A7818, UPI0001A61537, UPI00017A812D
EMBL: AK022604, AP005482, CH471113, EF445040, AL833727, AK303117, BC026307, AK298223, AK301964
Ensembl: ENSG00000101624
KO: hsa:79959
Nucleutide sequences
EMBL-CDS: BAG63377.1, CAH56252.1, BAG64223.1, EAX01543.1, ACA06091.1, AAH26307.1, BAB14123.1, BAG60493.1
Ensembl_TRS: ENST00000262127, ENST00000423709, ENST00000587929
Protein sequencees
Ensembl_PRO: ENSP00000262127, ENSP00000403074, ENSP00000466833
RefSeq: XP_016881474.1, XP_016881472.1, XP_016881471.1, XP_016881476.1, XP_016881475.1, NP_001258918.1, NP_079175.2, XP_016881473.1, XP_016881470.1, XP_005258206.1
Others
UniRef100: UniRef100_Q8TAP6, UniRef100_B4DP81
UniRef90: UniRef90_B4DP81, UniRef90_Q8TAP6
UniRef50: UniRef50_Q8TAP6, UniRef50_B4DP81
UniGene: Hs.236940
CCDS: CCDS62390.1, CCDS11861.1

全选

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