| Type | Description |
|---|---|
| Definition | adrenomedullin 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:37:00 | Protective effects of intermedin/adrenomedullin-2 in a cellular model of human pulmonary arterial hypertension. | 32017948 |
| 2020-08-01 14:37:00 | AM2 signaling is suppressed in adipose tissue in obesity, involving lower receptor expression and ligand availability, likely contributing to insulin resistance and other aspects of the pathophysiology associated with obesity. | 31642491 |
| 2020-01-25 10:18:00 | Consistent with this hypothesis, we showed that acylated truncated ADM/ADM2 analogs of 27-31 residues exhibit potent antagonistic activity toward CLR/RAMP1 and 2. | 31150417 |
| 2019-04-27 11:45:00 | Intermedin binds the RAMP1/CLR complex via a triple beta-turn. | 30139742 |
| 2019-04-20 10:49:00 | Study revealed that exogenous intermedin up-regulates the expression of VEGF and RAMP2 at least partially via activating Wnt/beta-catenin signaling, finally promoting angiogenesis of hypoxia and reoxygenation impaired HUVECs in vitro. | 30931679 |
| Type | IDs |
|---|---|
| Synonymous | AM2, dJ579N16.4 |
| Gene |
UniProtKB-ID:
ADM2_HUMAN
UniprotKB:
Q7Z4H4
UniParc:
UPI00001B5BFA
EMBL:
AL096767,
AB121034,
AF529213,
AB236970
Ensembl:
ENSG00000128165
KO:
hsa:79924
|
| Nucleutide sequences |
EMBL-CDS:
BAD07411.1,
BAE46395.1,
AAQ09100.1
Ensembl_TRS:
ENST00000395738,
ENST00000395737
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000379087,
ENSP00000379086
RefSeq:
NP_001240774.1,
NP_001356811.1
|
| Others |
UniRef100:
UniRef100_Q7Z4H4
UniRef90:
UniRef90_Q7Z4H4
UniRef50:
UniRef50_Q7Z4H4
UniGene:
Hs.449099,
Hs.743540
CCDS:
CCDS33682.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员