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79903 NAA60

79903

NAA60

N(alpha)-acetyltransferase 60, NatF catalytic subunit

protein-coding

Homo sapiens

基因描述

Type Description
Definition N(alpha)-acetyltransferase 60, NatF catalytic subunit

研究结论

Date Results Publications
2018-07-23 13:18:00 Results from a study on gene expression variability markers in early-stage human embryos shows that NAA60 (NAT15) is a putative expression variability marker for the 3-day, 8-cell embryo stage. 26288249
2018-05-05 10:10:00 The hNaa60 protein contains an amphipathic helix following its GNAT domain that may contribute to Golgi localization of hNaa60, and the beta7-beta8 hairpin adopted different conformations in the hNaa60(1-242) and hNaa60(1-199) crystal structures. 27550639
2017-06-24 11:39:00 analysis of the mode of cytosolic Naa60 anchoring to the Golgi apparatus, most likely occurring post-translationally and specifically facilitating post-translational N-terminal acetylation of many transmembrane proteins 28196861
2016-11-25 15:06:00 Knockdown of the N-terminal acetyltransferase Naa60 compromises Golgi ribbon integrity. 26164078
2016-11-25 15:04:00 The first crystal structure of the N-terminal acetyltransferase Naa60 reveals two elongated loops important for substrate-specific binding not found in other NAT structures. 27320834

名称对应

Type IDs
Synonymous HAT4, NAT15, NatF, hNaa60
Gene
UniProtKB-ID: NAA60_HUMAN, I3L153_HUMAN, A0A384NYU5_HUMAN
UniprotKB: Q9H7X0, I3L153, A0A384NYU5
UniParc: UPI000059D2FF, UPI00017A7454, UPI0001AE67F8, UPI000006E5CC, UPI00017A8201, UPI0000E025DC
EMBL: CH471112, AC025283, AC004224, BC011267, AK297219, AK092005, AK024216, CR457324, AK298566, AY358543, AK302361, GQ900980
Ensembl: ENSG00000122390
KO: hsa:79903
Nucleutide sequences
EMBL-CDS: AAH11267.1, EAW85362.1, BAG59702.1, EAW85358.1, EAW85361.1, BAG60760.1, AAQ88907.1, BAB14853.1, EAW85363.1, EAW85364.1, BAG63686.1, BAG52462.1, CAG33605.1, EAW85360.1, EAW85359.1, ADO22497.1
Gene_ORFName: UNQ2771/PRO7155
Ensembl_TRS: ENST00000421765, ENST00000577013, ENST00000424546, ENST00000573580, ENST00000572942, ENST00000572169, ENST00000572584, ENST00000649360, ENST00000407558, ENST00000575076, ENST00000360862, ENST00000649205, ENST00000570819, ENST00000414063, ENST00000576916
Protein sequencees
Ensembl_PRO: ENSP00000459057, ENSP00000458575, ENSP00000405873, ENSP00000459055, ENSP00000497988, ENSP00000354108, ENSP00000458928, ENSP00000385903, ENSP00000460763, ENSP00000461730, ENSP00000401237, ENSP00000393224, ENSP00000497411, ENSP00000458667, ENSP00000461703
RefSeq: NP_001304023.1, NP_001304024.1, NP_001304026.1, NP_001304027.1, NP_001304022.1, NP_001304025.1, NP_001077069.1, NP_001077070.1, NP_079121.1
Others
UniRef100: UniRef100_I3L153, UniRef100_Q9H7X0
UniRef90: UniRef90_Q9H7X0, UniRef90_G3SFD8
UniRef50: UniRef50_Q9H7X0, UniRef50_G3SFD8
UniGene: Hs.513296
CCDS: CCDS81941.1, CCDS81937.1, CCDS45396.1, CCDS81938.1, CCDS81939.1

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