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79882 ZC3H14

79882

ZC3H14

zinc finger CCCH-type containing 14

protein-coding

Homo sapiens

基因描述

Type Description
Definition zinc finger CCCH-type containing 14

研究结论

Date Results Publications
2020-02-15 10:10:00 study suggests that ZC3H14 functions as a novel tumor suppressor and is a candidate prognostic biomarker for hepatocellular carcinoma patients 30371740
2017-05-27 10:16:00 ATP5G1 turnover increases upon depletion of ZC3H14, double knockdown of ZC3H14 and the nonsense-mediated decay factor, UPF1, rescues ATP5G1 transcript levels. Furthermore, fractionation reveals an increase in the amount of ATP5G1 pre-mRNA that reaches the cytoplasm when ZC3H14 is depleted and that ZC3H14 binds to ATP5G1 pre-mRNA in the nucleus. 27563065
2014-06-07 10:26:00 we show here that human ZC3H14 can functionally substitute for dNab2 in fly neurons and can rescue defects in development and locomotion that are present in dNab2 null flies 24671764
2011-10-08 12:04:00 report a intellectual disability disease locus on chromosome 14q31.3 corresponding to mutation of the ZC3H14 gene that encodes a conserved polyadenosine RNA binding protein 21734151
2011-08-13 10:49:00 MSUT2 levels may influence neuronal vulnerability to tau toxicity and aggregation. 21355046

名称对应

Type IDs
Synonymous MRT56, MSUT-2, NY-REN-37, SUT2, UKp68
Gene
UniProtKB-ID: ZC3HE_HUMAN, A0A024R6F2_HUMAN, G3V256_HUMAN, G3V411_HUMAN
UniprotKB: Q6PJT7, A0A024R6F2, G3V256, G3V411
UniParc: UPI0000072560, UPI0001A4717A, UPI0000359525, UPI0002065447, UPI000041CD69, UPI0000EE33F8, UPI00004567B2, UPI000006D754, UPI00017221CF, UPI0000EE33F9, UPI000049DDC1, UPI000387DA0E, UPI00001BDB9B
EMBL: AY578062, AF155107, BX248281, AL834215, KF495808, AY578060, AK302136, BX640716, BX248265, BC027607, AK304275, BC011793, AK303123, AY578063, AY578061, AK021868, BC023641, CH471061, AF474376, BX248769, BX640876, AL162171
Ensembl: ENSG00000100722
KO: hsa:79882
Nucleutide sequences
EMBL-CDS: CAD66576.1, AAH27607.1, CAD62593.1, CAE45835.1, AAH23641.1, AAS90301.1, EAW81390.1, EAW81389.1, AAL83289.1, EAW81388.1, AAS90300.1, AAD42873.1, AAS90302.1, CAD62609.1, BAG63510.1, AAH11793.1, BAG65136.1, AAS90299.1, BAG64229.1, CAE45933.1, EAW81385.1, CAD38897.1, EAW81384.1, EAW81387.1, EAW81391.1
Gene_ORFName: hCG_21080, hCG_21080
Ensembl_TRS: ENST00000555755, ENST00000318308, ENST00000336693, ENST00000251038, ENST00000406216, ENST00000393514, ENST00000302216, ENST00000556945, ENST00000555900
Protein sequencees
Ensembl_PRO: ENSP00000452475, ENSP00000384682, ENSP00000327176, ENSP00000377150, ENSP00000338002, ENSP00000307025, ENSP00000251038, ENSP00000450474, ENSP00000451530
RefSeq: NP_001313233.1, NP_001313230.1, NP_001313229.1, XP_005268127.1, NP_079100.2, NP_001313232.1, XP_005268130.1, NP_001313245.1, NP_001313244.1, NP_997543.1, NP_001313243.1, NP_001313242.1, NP_001313237.1, XP_011535464.1, NP_997545.2, XP_011535463.1, NP_997544.1, XP_006720320.1, NP_001153575.1, XP_024305481.1, NP_001313234.1, NP_001313235.1, NP_001313226.1, NP_001153576.1, NP_001313228.1, NP_001313238.1, NP_001313225.1, NP_001313239.1, NP_001313240.1, NP_001313227.1, NP_001313241.1, NP_001313231.1, NP_001313224.1, NP_001313236.1
Others
UniRef100: UniRef100_A0A024R6F2, UniRef100_G3V411, UniRef100_G3V256, UniRef100_Q6PJT7
UniRef90: UniRef90_Q6PJT7, UniRef90_Q6PJT7-10, UniRef90_A0A4X1SWS2
UniRef50: UniRef50_Q6PJT7-10, UniRef50_A0A4X1SWS2, UniRef50_Q6PJT7
UniGene: Hs.686171
CCDS: CCDS32134.1, CCDS55938.1, CCDS86418.1, CCDS32136.1, CCDS32133.1, CCDS32135.1

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