| Type | Description |
|---|---|
| Definition | Rho guanine nucleotide exchange factor 5 |
| Date | Results | Publications |
|---|---|---|
| 2016-06-28 11:47:00 | Tim protein and DDX11 physically and functionally interact and act in concert to preserve replication fork progression in perturbed conditions. | 26503245 |
| 2016-05-14 12:17:00 | Data indicate that Rho guanine nucleotide exchange factor 5 (ARHGEF5) is expressed in most human lung adenocarcinoma tissues and cell lines. | 25777963 |
| 2016-02-06 12:21:00 | Targeting rho guanine nucleotide exchange factor ARHGEF5/TIM with auto-inhibitory peptides in human breast cancer. | 25743165 |
| 2015-12-05 11:22:00 | The auto-inhibitory state of Rho guanine nucleotide exchange factor ARHGEF5/TIM can be relieved by targeting its SH3 domain with rationally designed peptide aptamers. | 25645980 |
| 2014-05-17 13:06:00 | In conclusion, ARHGEF5/Src can be considered as a prognostic biomarker and a therapeutic target for patients with resected NSCLC. | 24126923 |
| Type | IDs |
|---|---|
| Synonymous | GEF5, P60, TIM, TIM1 |
| Gene |
UniProtKB-ID:
ARHG5_HUMAN
UniprotKB:
Q12774
UniParc:
UPI0000000CA5,
UPI00004028DC
EMBL:
BC014555,
BC011839,
BC010046,
U02082,
CH471146,
AK160365,
AC004534
Ensembl:
ENSG00000050327
KO:
hsa:7984
|
| Nucleutide sequences |
EMBL-CDS:
AAH11839.1,
AAC12958.1,
AAH10046.1,
AAH14555.1,
BAD18708.1,
AAA18010.1,
EAW80096.1
Ensembl_TRS:
ENST00000056217,
ENST00000471847
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000418227,
ENSP00000056217
RefSeq:
XP_016868112.1,
NP_005426.2
|
| Others |
UniRef100:
UniRef100_Q12774
UniRef90:
UniRef90_Q12774
UniRef50:
UniRef50_Q12774
UniGene:
Hs.334,
Hs.534621
CCDS:
CCDS34771.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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