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79834 PEAK1

79834

PEAK1

pseudopodium enriched atypical kinase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition pseudopodium enriched atypical kinase 1

研究结论

Date Results Publications
2020-09-19 16:28:00 AXL confers cell migration and invasion by hijacking a PEAK1-regulated focal adhesion protein network. 32681075
2020-04-11 10:36:00 PEAK1 functions as a tumor promoter in colorectal cancer cells, and its expression is regulated by the EGFR/KRas signaling axis and miR-181d. 29449544
2019-12-07 12:41:00 PEAK1 overexpression could induce epithelial-to-mesenchymal transition (EMT) and the expression of matrix metalloproteinase-2 (MMP2) and MMP9 both in vitro and in vivo, whereas PEAK1 knockout had the opposite effects. 30038287
2019-11-02 13:01:00 PEAK1-PPP1R12B axis inhibits colorectal tumorigenesis and metastasis through deactivation of the Grb2/PI3K/Akt pathway. 30472186
2019-05-25 10:32:00 PEAK1 protein level is increased during pancreatic ductal adenocarcinoma progression with the highest levels of expression observed in metastatic cell populations.Kras protein expression is controlled by a self-regulating feedforward mechanism mediated by eIF5A-PEAK1. 29321164

名称对应

Type IDs
Synonymous SGK269
Gene
UniProtKB-ID: PEAK1_HUMAN
UniprotKB: Q9H792
UniParc: UPI00002378D0
EMBL: AK024793, AC107883, AC087465, AK091802, AK074157, AK127658, AB082533
Ensembl: ENSG00000173517
KO: hsa:79834
Nucleutide sequences
EMBL-CDS: BAB84983.1, BAC87076.1, BAB15006.1, BAC02711.1
Ensembl_TRS: ENST00000560626, ENST00000312493
Protein sequencees
Ensembl_PRO: ENSP00000452796, ENSP00000309230
RefSeq: XP_011520338.1, XP_024305826.1, XP_005254727.1, XP_011520342.1, XP_024305829.1, XP_011520344.1, XP_024305827.1, XP_011520340.1, NP_001371956.1, XP_005254730.1, XP_011520337.1, XP_011520343.1, XP_024305824.1, XP_011520335.1, NP_001374014.1, NP_001374015.1, XP_005254728.1, XP_024305832.1, XP_005254731.1, NP_001371955.1, XP_024305828.1, XP_011520339.1, XP_005254732.1, NP_079052.2, XP_024305830.1, XP_011520341.1, XP_024305831.1, XP_024305825.1, XP_011520336.1
Others
UniRef100: UniRef100_Q9H792
UniRef90: UniRef90_Q9H792
UniRef50: UniRef50_Q9H792
UniGene: Hs.9587, Hs.731402
CCDS: CCDS42062.1

全选

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