| Type | Description |
|---|---|
| Definition | lysine demethylase 8 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:17:00 | JMJD5 couples with CDK9 to release the paused RNA polymerase II. | 32747552 |
| 2020-09-19 16:28:00 | Downregulation of Jumonji-C domain-containing protein 5 inhibits proliferation by silibinin in the oral cancer PDTX model. | 32678829 |
| 2019-09-28 10:11:00 | Recognition between JMJD5/JMJD7 and histone substrates is specific, which is reflected by the binding data between enzymes and substrates. High structural similarity between JMJD5 and JMJD7 is reflected by the shared common substrates and high binding affinity. | 29459673 |
| 2019-04-06 12:07:00 | JMJD5 expression is increased in oral squamous cell carcinoma tissue samples and tumor cell lines. | 30551455 |
| 2019-03-16 10:26:00 | KDM8/JMJD5exhibits a novel property as a dual coactivator of AR and PKM2 and as such, it is a potent inducer of castration and therapy resistance.Its oncogenic properties in prostate cancer come from its direct interaction with AR to affect androgen response and with PKM2 to regulate tumor metabolism. | 30072740 |
| Type | IDs |
|---|---|
| Synonymous | JMJD5 |
| Gene |
UniProtKB-ID:
KDM8_HUMAN,
A0A0S2Z5P8_HUMAN,
A0A0S2Z5T1_HUMAN
UniprotKB:
Q8N371,
A0A0S2Z5P8,
A0A0S2Z5T1
UniParc:
UPI0000071B08,
UPI000720F7AB,
UPI00001BB9EC,
UPI00017A73AE
EMBL:
AC092725,
KU178786,
AC109449,
AC106739,
CH471145,
AK297166,
AY345239,
AK023860,
BC027911,
KU178785
Ensembl:
ENSG00000155666
KO:
hsa:79831
|
| Nucleutide sequences |
EMBL-CDS:
BAB14706.1,
AAH27911.1,
BAG59661.1,
AAQ23080.1,
ALQ34244.1,
ALQ34243.1,
EAW55759.1
Gene_ORFName:
hCG_22645
Ensembl_TRS:
ENST00000568965,
ENST00000441782,
ENST00000286096
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000286096,
ENSP00000456901,
ENSP00000398410
RefSeq:
XP_016879169.1,
NP_079049.2,
XP_016879168.1,
XP_016879166.1,
XP_016879165.1,
NP_001138820.1,
XP_016879167.1
|
| Others |
UniRef100:
UniRef100_Q8N371,
UniRef100_A0A0S2Z5P8
UniRef90:
UniRef90_A0A2K5I719,
UniRef90_Q8N371
UniRef50:
UniRef50_Q8N371,
UniRef50_A0A2K6KEL7
UniGene:
Hs.145717
CCDS:
CCDS10627.1,
CCDS45448.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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