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79828 METTL8

79828

METTL8

methyltransferase like 8

protein-coding

Homo sapiens

基因描述

Type Description
Definition methyltransferase like 8

研究结论

Date Results Publications
2017-09-30 10:29:00 Data, including data from studies using mutant/knockout mice and cell lines from such mice, suggest that METTL2 and METTL6 (but not METTL8) contribute to post-transcriptional methylation of cytidine (formation of 3-methylcytidine) in tRNA; METTL2 methylates tRNA(Thr) and tRNA(Arg); METTL6 interacts with seryl-tRNA synthetase and methylates tRNA(Ser); METTL8 catalyzes post-transcriptional methylation of cytidine in mRNA. 28655767

名称对应

Type IDs
Synonymous TIP
Gene
UniProtKB-ID: METL8_HUMAN, B4DLT0_HUMAN, A8K7U3_HUMAN, B3KW44_HUMAN
UniprotKB: Q9H825, B4DLT0, A8K7U3, B3KW44
UniParc: UPI0000072472, UPI00017A737F, UPI00015DA9DD, UPI00001AF3AB, UPI00004A24F5
EMBL: AK024046, AC008065, CH471058, AK297141, KF459614, AK292108, BC025250, AC007739, AC007969, AK124092
Ensembl: ENSG00000123600
KO: hsa:79828
Nucleutide sequences
EMBL-CDS: EAX11215.1, AAX93284.1, BAB14797.1, AAH25250.1, AAX93077.1, BAG59642.1, BAF84797.1, BAG54006.1, EAX11217.1, EAX11214.1
Gene_ORFName: hCG_2004932
Ensembl_TRS: ENST00000447486, ENST00000392604, ENST00000612742
Protein sequencees
Ensembl_PRO: ENSP00000376382, ENSP00000409025, ENSP00000480056
RefSeq: NP_001308083.1, NP_001308086.1, NP_001308084.1, XP_011510177.1, NP_001308088.1, NP_001308091.1, NP_001308090.1, XP_016860477.1, XP_016860473.1, NP_001308089.1, NP_079046.2, XP_016860474.1, XP_016860478.1, NP_001308085.1, XP_016860475.1, XP_016860476.1, NP_001308087.1
Others
UniRef100: UniRef100_B4DLT0, UniRef100_B3KW44, UniRef100_A8K7U3, UniRef100_Q9H825
UniRef90: UniRef90_F6W273, UniRef90_Q9H825, UniRef90_B3KW44
UniRef50: UniRef50_Q9H825, UniRef50_A2AUU0-6, UniRef50_A2AUU0-3
UniGene: Hs.135146
CCDS: CCDS82532.1, CCDS82531.1

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