| Type | Description |
|---|---|
| Definition | TLE family member 6, subcortical maternal complex member |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 13:03:00 | Expanding the genetic and phenotypic spectrum of female infertility caused by TLE6 mutations. | 31897846 |
| 2016-07-16 11:13:00 | In this first report of a human defect in a member of the subcortical maternal subcritical maternal complex, we show that the TLE6 mutation is gender-specific and leads to the earliest known human embryonic lethality phenotype | 26537248 |
| 2014-07-12 10:52:00 | transcriptional programmes regulated by FOXG1 and Groucho/TLE are important for BTIC-initiated brain tumour growth, implicating FOXG1 and Groucho/TLE in GBM tumourigenesis | 24356439 |
| 2010-01-21 00:00:00 | Expression of Tle6-like in colon cancer cells increased cell proliferation, colony-formation, cell migration, and xenograft tumorgenicity. | 18551179 |
| Type | IDs |
|---|---|
| Synonymous | GRG6, PREMBL |
| Gene |
UniProtKB-ID:
TLE6_HUMAN,
Q6PJM9_HUMAN
UniprotKB:
Q9H808,
Q6PJM9
UniParc:
UPI00001BDA02,
UPI000007242D,
UPI000059D62B
EMBL:
BC013986,
BC020206,
AC006277,
AK024071,
BC007215,
AC007766
Ensembl:
ENSG00000104953
KO:
hsa:79816
|
| Nucleutide sequences |
EMBL-CDS:
BAB14815.1,
AAH07215.1,
AAH20206.1,
AAH13986.1
Ensembl_TRS:
ENST00000246112,
ENST00000452088
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000246112,
ENSP00000406893
RefSeq:
XP_024307490.1,
XP_024307491.1,
XP_024307492.1,
NP_079036.1,
XP_011526603.1,
XP_011526602.1,
XP_005259702.1,
NP_001137458.1
|
| Others |
UniRef100:
UniRef100_Q9H808,
UniRef100_Q6PJM9
UniRef90:
UniRef90_A0A2R9A736,
UniRef90_Q9H808
UniRef50:
UniRef50_Q9H808,
UniRef50_A0A2R9A736
UniGene:
Hs.334507
CCDS:
CCDS12100.1,
CCDS45910.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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