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79800 CARF

79800

CARF

calcium responsive transcription factor

protein-coding

Homo sapiens

基因描述

Type Description
Definition calcium responsive transcription factor

研究结论

Date Results Publications
2019-11-02 13:25:00 Wi-A caused upregulation of CARF (collaborator of ARF) demonstrating an activation of DNA damage oxidative stress response in both cancer and normal cells. In line with this, upregulation of p21WAF1, p16INK4A, and hypophosphorylated pRB and induction of senescence were observed demonstrating that Wi-A-induced senescence is mediated by multiple pathways in which CARF-mediated DNA damage and oxidative stress play a major ro 29718136
2018-11-24 11:21:00 Data demonstrate that CARF is a new target of miR-451 that mediates its tumor suppressor function in normal and stressed biological states. 29321561
2003-03-21 14:59:00 Cloned as a calcium- and neural-selective transcriptional activator of the gene for Brain-Derived Neurotrophic Factor (BDNF). 11832226

名称对应

Type IDs
Synonymous ALS2CR8, NYD-SP24
Gene
UniProtKB-ID: CARTF_HUMAN, A0A024R405_HUMAN, C9JI92_HUMAN, B4DIA7_HUMAN
UniprotKB: Q8N187, A0A024R405, C9JI92, B4DIA7
UniParc: UPI00002093E9, UPI00017A727B, UPI0000072144, UPI0000EE372A, UPI000007284D
EMBL: AC010900, AY032876, AB053310, AK025232, AK304014, AK295499, CH471063, BC033777, AL834188, AF454946, AB053309
Ensembl: ENSG00000138380
KO: hsa:79800
Nucleutide sequences
EMBL-CDS: CAD38882.2, AAY24288.1, BAG64929.1, BAB69019.1, AAH33777.1, BAB15088.1, AAK66819.2, BAB69018.1, AAL62330.1, EAW70320.1, EAW70321.1, EAW70323.1, EAW70324.1, BAG58419.1
Gene_ORFName: hCG_1779945
Ensembl_TRS: ENST00000402905, ENST00000434998, ENST00000428585, ENST00000320443, ENST00000438828, ENST00000414439
Protein sequencees
Ensembl_PRO: ENSP00000414644, ENSP00000384006, ENSP00000396221, ENSP00000415948, ENSP00000316224, ENSP00000416160
RefSeq: NP_001269840.1, XP_016860455.1, XP_016860454.1, NP_001339605.1, XP_011510170.1, XP_016860453.1, NP_001098056.1, NP_001309357.1, XP_006712823.1, XP_011510171.1, XP_011510169.1, XP_024308918.1, NP_001309358.1, NP_079020.13, XP_005246915.1, NP_001309356.1, XP_005246916.1, XP_024308919.1, NP_001339607.1, NP_001339608.1, NP_001269841.1, NP_001339606.1, XP_016860452.1, XP_016860451.1, NP_001269839.1
Others
UniRef100: UniRef100_B4DIA7, UniRef100_Q8N187
UniRef90: UniRef90_Q8N187
UniRef50: UniRef50_Q8N187
UniGene: Hs.444982
CCDS: CCDS63091.1, CCDS42801.1

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