| Type | Description |
|---|---|
| Definition | F-box protein 31 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:16:00 | Mutations disrupting neuritogenesis genes confer risk for cerebral palsy. | 32989326 |
| 2020-11-21 13:26:00 | F-box protein FBXO31 modulates apoptosis and epithelial-mesenchymal transition of cervical cancer via inactivation of the PI3K/AKT-mediated MDM2/p53 axis. | 32800832 |
| 2020-06-13 12:36:00 | FBXO31 plays a pivotal role in preserving genomic integrity by maintaining low cyclin A levels during the G1 phase for faithful genome duplication and segregation | 31413110 |
| 2019-07-27 12:28:00 | Higher mRNA expression levels of FBXO1, FBXO31, SKP2, and FBXO5 were significantly associated with worse prognosis for breast cancer patients. (Review) | 30341246 |
| 2019-01-12 10:35:00 | Results identified FBXO31 as a novel E3 ubiquitin ligase of Snail1, and its low expression contributes to an aberrant accumulation of Snail1 in gastric cancer. Furthermore, F-box domain of FBXO31 and the phosphorylation of Snail1 are essential for the interaction and degradation. These findings reveal the important function of FBXO31 on the regulation of Snail1 protein level in gastric cancer. | 29117943 |
| Type | IDs |
|---|---|
| Synonymous | FBX14, FBXO14, Fbx31, MRT45, pp2386 |
| Gene |
UniProtKB-ID:
FBX31_HUMAN,
A0A0C4DGU8_HUMAN
UniprotKB:
Q5XUX0,
A0A0C4DGU8
UniParc:
UPI0000052203,
UPI000021D235,
UPI000059D3D0
EMBL:
AF428140,
AC010531,
BC012748,
AY736035,
AL117444,
AF318348,
CH471114
Ensembl:
ENSG00000103264
KO:
hsa:79791
|
| Nucleutide sequences |
EMBL-CDS:
CAB55929.2,
AAH12748.1,
AAU50679.1,
AAL55855.1,
AAQ04213.1,
EAW95400.1
Gene_ORFName:
PP2386,
hCG_1980666
Ensembl_TRS:
ENST00000311635,
ENST00000618298
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000310841,
ENSP00000479703
RefSeq:
NP_079011.3,
NP_001269612.1
|
| Others |
UniRef100:
UniRef100_Q5XUX0,
UniRef100_A0A0C4DGU8
UniRef90:
UniRef90_Q5XUX0
UniRef50:
UniRef50_Q5XUX0
UniGene:
Hs.567582
CCDS:
CCDS32501.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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