| Type | Description |
|---|---|
| Definition | mitochondrial transcription termination factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-06-24 12:25:00 | MTERF1 has the ability to accommodate alternate active conformations. | 26523681 |
| 2017-06-10 12:12:00 | It has been demonstrated that MTERF1 arrests mitochondrial DNA (mtDNA) replication with distinct polarity whereby MTERF1 acts as a directional contra-helicase, blocking mtDNA unwinding by the mitochondrial helicase TWINKLE. | 27112570 |
| 2012-06-23 10:47:00 | Studies indicate that the structure of the mitochondrial transcription termination factor (MTERF1) provides insight into the mechanism of binding, recognition of the termination sequence and the conformational changes involved in mediating termination. | 21326908 |
| 2011-10-01 11:25:00 | Single nucleotide polymorphism in MTERF gene is associated with epithelial ovarian cancer. | 21447778 |
| 2011-08-27 10:37:00 | data suggested that hMTERF4 is an essential factor for cell proliferation, which is probably modulated by mitochondrial transcription to promote cell proliferation | 21450691 |
| Type | IDs |
|---|---|
| Synonymous | MTERF |
| Gene |
UniProtKB-ID:
MTEF1_HUMAN,
B4DPR9_HUMAN
UniprotKB:
Q99551,
B4DPR9
UniParc:
UPI000020F528,
UPI000004A0C8
EMBL:
AK298469,
AK222730,
AC000056,
BC130389,
BC000965,
AC003086,
CH236949,
Y09615,
AC002564,
BC108648,
CH471091,
KF511051,
BC130391
Ensembl:
ENSG00000127989
KO:
hsa:7978
|
| Nucleutide sequences |
EMBL-CDS:
EAL24159.1,
EAW76869.1,
AAB83941.1,
CAA70830.1,
AAI30392.1,
AAI08649.1,
AAH00965.1,
AAI30390.1,
BAD96450.1,
BAG60681.1
Ensembl_TRS:
ENST00000351870,
ENST00000419292,
ENST00000406735
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000248643,
ENSP00000414116,
ENSP00000384986
RefSeq:
XP_005250650.1,
NP_008911.1,
XP_016868109.1,
NP_001288064.1,
XP_006716189.1,
NP_001288063.1
|
| Others |
UniRef100:
UniRef100_Q99551
UniRef90:
UniRef90_Q99551
UniRef50:
UniRef50_Q99551
UniGene:
Hs.532216
CCDS:
CCDS5621.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 27112570 |
Mitochondrial transcription termination factor 1 directs polar replication fork pausing. Nucleic Acids Res Yonghong Shi , Viktor Posse , Xuefeng Zhu , Anne K Hyvärinen , Howard T Jacobs , Maria Falkenberg , Claes M Gustafsson |
2016-07-08 | - |
| 26523681 |
Base Flipping by MTERF1 Can Accommodate Multiple Conformations and Occurs in a Stepwise Fashion. J. Mol. Biol. James Byrnes , Kevin Hauser , Leah Norona , Edison Mejia , Carlos Simmerling , Miguel Garcia-Diaz |
2016-06-19 | - |
| 26496610 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , Jürgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , Jörg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann |
2015-10-22 |
Cep85l,
Rcc1,
Zbtb48,
Bsdc1,
Kifc1,
Ccp110,
Ints4,
Slc6a8,
Cenpi,
Nup107,
Xpo1,
Fbxw11,
Tubg1,
Csnk1d,
Bap1,
Ptpn23,
Tecpr2,
Slain1,
Ankrd28,
Prkaa1,
Espl1,
Gbf1,
Cdc20,
Cenpf,
Trip11,
Mbd5,
Kif22,
Dut,
Srsf1,
Actb,
Spred2,
Akt2,
Mta1,
Tgs1,
Pip4k2c,
Ankfy1,
Apc,
Ar,
Rhoa,
Atp2a2,
Atp5a1,
Atp7a,
Cep131,
Bach1,
Bcl7c,
Bmpr1a,
Brca1,
Bub1,
Bub1b,
C1qbp,
Anxa2,
Calu,
Cbx1,
Cbx4,
Cct2,
Cct3,
Cct4,
Cct7,
Cct8,
Cd2ap,
Cdk1,
Cdc37,
Cdh1,
Chek1,
Cit,
Copa,
Crebbp,
Cry1,
Csk,
Smc3,
Dctn1,
Ddb1,
Cdk2ap1,
Mapre1,
Ect2,
Eef1a1,
Eif3a,
Mark2,
Evpl,
Ewsr1,
Wdr5,
Dclre1b,
Fbl,
Fgfr1,
Flot1,
Flot2,
B4galt1,
Gnb1,
Gspt1,
Hdac6,
Herc2,
Hsf1,
Hsph1,
Elavl1,
Id2,
Cyr61,
Cep250,
Insr,
Eif3e
|
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 25609649 |
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. Mol. Syst. Biol. Xu Li , Wenqi Wang , Jiadong Wang , Anna Malovannaya , Yuanxin Xi , Wei Li , Rudy Guerra , David H Hawke , Jun Qin , Junjie Chen |
2015-01-01 |
ABI1,
ZBTB33,
TCF24,
RPL29P11,
FOXO6,
HDAC6,
HDAC5,
MEF2B,
CHAF1A,
PARP2,
HMGXB4,
SMC4,
FARSB,
HUWE1,
RAD50,
SUGP2,
ABI2,
WASF2,
ALYREF,
TSHZ1,
DDX39A,
TRIB1,
GPHN,
AKAP8,
STAG1,
SF3A1,
TNIP1,
ADAR,
HMG20B,
IRF9,
MYL12B,
MYL9,
CFDP1,
MCRS1,
TOMM40,
CDX2,
COG5,
HOXB13,
LRRC41,
NCOA2,
CEBPB,
KAT5,
SLU7,
DRAP1,
SMC2,
CENPB,
PRPF8,
MXD4,
P3H4,
TRIM3,
ARID3B,
STAG2,
NCKAP1,
IQGAP2,
ZNF268,
UTP14A,
MRPS30,
BRD8,
TCERG1,
MORF4,
POP1,
SF3A3,
SF3B2,
KIF2C,
ATF7,
TMED1,
RCC1,
DDX52,
CHD4,
FOXN3,
PSIP1,
WDHD1,
CHI3L2,
BAZ1A,
NISCH,
CHEK2,
MRPL3,
PNKP,
SGF29,
NACC1,
ACOT7,
LACTB,
DNTTIP1,
FOXP4,
IKBIP,
JDP2,
ANKRD26P1,
HEXIM2,
C17orf49,
NDUFA11,
PUSL1,
COPA,
MAP3K8,
LIN54,
C5orf24,
COX7A2,
CPOX,
CPS1,
NACC2
|
| 25798074 |
Proteome Sci Fernanda Luisa Basei , Gabriela Vaz Meirelles , Germanna Lima Righetto , Deivid Lucas Dos Santos Migueleti , Juliana Helena Costa Smetana , Jörg Kobarg |
2015-01-01 | - |
| 24598254 |
A bifunctional protein regulates mitochondrial protein synthesis. Nucleic Acids Res. Tara R Richman , Stefan M K Davies , Anne-Marie J Shearwood , Judith A Ermer , Louis H Scott , Moira E Hibbs , Oliver Rackham , Aleksandra Filipovska |
2014-05-01 |
AUH,
MTERF1
|
| 22681889 |
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Mol. Cell Alexander G Baltz , Mathias Munschauer , Björn Schwanhäusser , Alexandra Vasile , Yasuhiro Murakawa , Markus Schueler , Noah Youngs , Duncan Penfold-Brown , Kevin Drew , Miha Milek , Emanuel Wyler , Richard Bonneau , Matthias Selbach , Christoph Dieterich , Markus Landthaler |
2012-06-08 |
NBPF10,
TSFM,
LRPPRC,
RBM12,
G3BP1,
SUGP2,
MBNL2,
CEBPZ,
TRIM28,
RBM7,
RBM6,
RBM5,
ALYREF,
MPHOSPH10,
EIF1,
DDX39A,
HNRNPR,
MRPS31,
POP7,
SRRM1,
SF3B4,
AKAP8,
LOC400927-CSNK1E,
SAP18,
EIF1B,
SF3A1,
CDKN2A,
ADAR,
NPM3,
RACK1,
NSA2,
ADARB1,
RBM14,
EMG1,
NXF1,
SYNCRIP,
MYBBP1A,
DDX17,
CHERP,
NOP56,
PRPF8,
IGF2BP1,
IGF2BP3,
IGF2BP2,
KHDRBS3,
KHDRBS1,
CELF1,
CELF2,
KIF1C,
SRSF10,
UTP14A,
CPSF4,
TCERG1,
RNPS1,
SUB1,
SRSF8,
SF3A3,
HNRNPA0,
EBNA1BP2,
CKAP4,
ASCC3,
GCN1,
SF3B2,
NUDT21,
CPSF6,
DDX52,
CHD2,
DUSP14,
DIDO1,
NUPL2,
HNRNPUL1,
KRR1,
LSM6,
PSIP1,
STRAP,
SUPT16H,
MRPL3,
ATXN2L,
LARP4,
DDX42,
PDAP1,
U2AF2,
WBSCR22,
KCTD12,
CIRBP,
MRPL54,
FTSJ3,
EXOSC6,
CHCHD1,
CLK3,
CLTC,
HIST4H4,
ZC3H18,
MSI2,
MRPL10,
RAVER1,
C1orf131,
RBM45,
CPEB2
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员