| Type | Description |
|---|---|
| Definition | TBC1 domain family member 17 |
| Date | Results | Publications |
|---|---|---|
| 2015-11-28 11:24:00 | Demonstrate that TBC1D15 and TBC1D17 mediate proper autophagic encapsulation of mitochondria by regulating Rab7 activity at the interface between mitochondria and isolation membranes. | 24569479 |
| 2013-06-15 10:34:00 | Optineurin acts as an adaptor to bring together Rab8 and its GTPase-activating protein TBC1D17. | 22854040 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
TBC17_HUMAN
UniprotKB:
Q9HA65
UniParc:
UPI000013C7D2,
UPI00020651DC,
UPI00042DB65E
EMBL:
AC118341,
AC118342,
BC003516,
AK300007,
AK022230,
AB449903
Ensembl:
ENSG00000104946
KO:
hsa:79735
|
| Nucleutide sequences |
EMBL-CDS:
BAB13991.1,
AAH03516.1,
BAH16646.1,
BAG61824.1
Ensembl_TRS:
ENST00000535102,
ENST00000221543
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000446323,
ENSP00000221543
RefSeq:
XP_011525619.1,
NP_001161694.1,
NP_078958.2
|
| Others |
UniRef100:
UniRef100_Q9HA65
UniRef90:
UniRef90_Q9HA65
UniRef50:
UniRef50_Q9HA65
UniGene:
Hs.631587
CCDS:
CCDS54294.1,
CCDS12785.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32877691 |
A High-Density Human Mitochondrial Proximity Interaction Network. Cell Metab Hana Antonicka , Zhen-Yuan Lin , Alexandre Janer , Mari J Aaltonen , Woranontee Weraarpachai , Anne-Claude Gingras , Eric A Shoubridge |
2020-09-01 | - |
| 31723608 |
Sci Adv Jin-Mi Heo , Nathan J Harper , Joao A Paulo , Mamie Li , Qikai Xu , Margaret Coughlin , Stephen J Elledge , J Wade Harper |
2019-11-01 | - |
| 28986522 |
Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism. Nat Commun Giulia Antoniali , Fabrizio Serra , Lisa Lirussi , Mikiei Tanaka , Chiara D'Ambrosio , Shiheng Zhang , Slobodanka Radovic , Emiliano Dalla , Yari Ciani , Andrea Scaloni , Mengxia Li , Silvano Piazza , Gianluca Tell |
2017-10-06 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 28378594 |
Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations. J. Proteome Res. Stefano Sala , Marleen Van Troys , Sandrine Medves , Marie Catillon , Evy Timmerman , An Staes , Elisabeth Schaffner-Reckinger , Kris Gevaert , Christophe Ampe |
2017-04-20 | - |
| 26389662 |
Nat. Cell Biol. Malavika Raman , Mikhail Sergeev , Maija Garnaas , John R Lydeard , Edward L Huttlin , Wolfram Goessling , Jagesh V Shah , J Wade Harper |
2015-10-01 |
myl7,
ubxn7,
ubxn10,
TIMM23,
ABCF2,
CDK4,
TOPORS,
TIMM17B,
STUB1,
UBE4B,
TUBB3,
UNC13B,
POLD3,
SEC24A,
PNPLA6,
TMED2,
ILVBL,
SLC27A4,
IFT27,
FAF1,
LACTB,
BTBD9,
KLHDC3,
UBXN10,
ADK,
UBXN2B,
CSNK1E,
CSNK1G3,
SLC25A10,
CSTF1,
TTC30B,
PPP4R2,
FAM91A1,
UBXN2A,
DSC1,
DSG1,
ELAVL2,
ERCC3,
ALDH1B1,
ABCB7,
ALDH9A1,
ALDH3A2,
KLHDC10,
UNC13A,
CLUAP1,
EMC1,
MYCBP2,
EPB41L3,
UBXN4,
FAF2,
VPS13A,
ABCF1,
UBR2,
GCAT,
TRAM1,
KLHDC2,
HSPBP1,
MTCH2,
YTHDF3,
KCTD13,
BRWD3,
UBXN7,
TRAF3IP1,
GCDH,
RANBP6,
ATP2C1,
HTRA2,
ACAD9,
IFT81,
SLC25A4,
GSK3B,
MSH6,
MYLPF,
PYCR2,
HLA-B,
HLA-C,
HMGB1,
MMAB,
HSPA2,
UBAC2,
IDE,
ACADM,
ACTBL2,
ACADSB,
ARAF,
STT3A,
JUN,
JUP,
KIFC1,
KPNA3,
MSH2,
MYO6,
NDUFS2,
ATP2B2,
ATP2B3,
NUP98,
ATP4A,
P4HB,
DERL2
|
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 26673895 |
A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Elife Koray Kırlı , Samir Karaca , Heinz Jürgen Dehne , Matthias Samwer , Kuan Ting Pan , Christof Lenz , Henning Urlaub , Dirk Görlich |
2015-01-01 |
CHA1,
KRR1,
SRO9,
STE50,
RRP7,
RNQ1,
DCC1,
GBP2,
SAT4,
RVS161,
YCR016W,
PWP2,
SSK22,
SOL2,
PAT1,
YCR087C-A,
OCA4,
MOB2,
EPL1,
BUD27,
FRS2,
LOC1,
YFR016C,
LSB3,
RPL2A,
PHO4,
SAP155,
IRC6,
ENT4,
PRP19,
RIX7,
YLL032C,
FRA1,
ISA1,
SPA2,
PUF3,
RPL8B,
NOC3,
SSL1,
SSK1,
NSE1,
RLP24,
SDO1,
ADE16,
RPL15A,
STU2,
RPS0B,
FRS1,
BMT6,
KIN2,
HRT3,
REX3,
YLR108C,
CFT2,
MSL5,
ACE2,
STM1,
YLR157C-A,
APS1,
CBF5,
SWI6,
SKG3,
HCR1,
PWP1,
NOP56,
BUR2,
GPN3,
DBP9,
GCD7,
SGD1,
STE11,
NMD4,
RPS22B,
ROM2,
STP3,
IKI3,
REH1,
AFG2,
UTP21,
ATG17,
TUS1,
MAG2,
ATG23,
RPS1A,
FPR4,
PDP3,
CDC24,
RBG1,
FUN12,
MTW1,
PRP45,
MAK16,
ECM1,
GPB2,
VPS8,
KIN3,
CDC15,
YAT1,
WHI4
|
| 24639526 |
RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling. Proc. Natl. Acad. Sci. U.S.A. Kendra S Carmon , Xing Gong , Jing Yi , Anthony Thomas , Qingyun Liu |
2014-04-01 |
Iqgap1,
SMC4,
LRPPRC,
TUBA1B,
CDX1,
N4BP2L2,
MYBBP1A,
DDX17,
PRPF8,
TBL3,
KHDRBS1,
WDR4,
ASCC3,
GCN1,
IMMT,
CHD3,
CHD4,
NISCH,
TUBA3E,
FTSJ3,
ANTXR2,
CLTC,
ZC3H18,
IQGAP3,
TRIM40,
CPD,
CPT1A,
LSM14B,
USP54,
DCTN1,
DDX3X,
DHX9,
DIAPH1,
DMPK,
AGL,
ABAT,
DSCAM,
DVL2,
EEF1A1,
EEF1A2,
EEF2,
ZFC3H1,
EIF4G1,
TUBB,
EPRS,
FASN,
PDCD11,
ACIN1,
CNOT1,
SNRNP200,
MYCBP2,
VWA8,
NUP205,
PRRC2C,
RRP12,
NUP210,
FKBP15,
NCAPD3,
DNAJC13,
SMCHD1,
FNBP4,
SF3B3,
SF3B1,
SCRIB,
EDC4,
GAK,
POLR1A,
GEMIN5,
PTPN23,
KIAA1429,
UPF2,
GIGYF2,
PELP1,
ZNF638,
GOLGA3,
RSPO1,
RGPD4,
SLC25A5,
NPC1L1,
CPSF1,
HDLBP,
HLA-DPB1,
HNRNPK,
HNRNPU,
HSPA2,
HSPD1,
IARS,
KRT79,
FBLL1,
ILF3,
KRT77,
KRT1,
KRT2,
KRT5,
KRT6A,
KRT9,
LAMC1,
LRP6,
MAP4
|
| 24569479 |
Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy. Elife Koji Yamano , Adam I Fogel , Chunxin Wang , Alexander M van der Bliek , Richard J Youle |
2014-01-01 |
TBC1D15,
TBC1D17
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
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