| Type | Description |
|---|---|
| Definition | partner and localizer of BRCA2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:47:00 | Missense PALB2 germline variant disrupts nuclear localization of PALB2 in a patient with breast cancer. | 32048105 |
| 2021-02-20 13:29:00 | Founder BRCA1/BRCA2/PALB2 pathogenic variants in French-Canadian breast cancer cases and controls. | 32300229 |
| 2021-02-06 13:52:00 | Functional characterization of 84 PALB2 variants of uncertain significance. | 31636395 |
| 2021-02-02 13:22:00 | Germline mutations of multiple breast cancer-related genes are differentially associated with triple-negative breast cancers and prognostic factors. | 32029870 |
| 2021-01-23 12:56:00 | USP22 Interacts with PALB2 and Promotes Chemotherapy Resistance via Homologous Recombination of DNA Double-Strand Breaks. | 31685642 |
| Type | IDs |
|---|---|
| Synonymous | FANCN, PNCA3 |
| Gene |
UniProtKB-ID:
PALB2_HUMAN,
H3BN63_HUMAN
UniprotKB:
Q86YC2,
H3BN63
UniParc:
UPI000000DA86,
UPI0000EE75DE
EMBL:
CR749637,
AK025469,
BC044254,
AL834425,
AC008870,
KC877588,
AK097533,
CH471145
Ensembl:
ENSG00000083093
KO:
hsa:79728
|
| Nucleutide sequences |
EMBL-CDS:
BAB15140.1,
CAD39086.1,
AAH44254.1,
EAW55813.1,
CAH18431.1,
BAC05090.1,
EAW55811.1
Gene_ORFName:
hCG_1986920
Ensembl_TRS:
ENST00000261584,
ENST00000568219
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000261584,
ENSP00000454703
RefSeq:
XP_016879162.1,
XP_011544249.1,
XP_011544248.1,
XP_016879160.1,
NP_078951.2,
XP_016879161.1,
XP_011544250.1
|
| Others |
UniRef100:
UniRef100_Q86YC2,
UniRef100_H3BN63
UniRef90:
UniRef90_Q86YC2
UniRef50:
UniRef50_Q86YC2
UniGene:
Hs.444664
CCDS:
CCDS32406.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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