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79723 SUV39H2

79723

SUV39H2

suppressor of variegation 3-9 homolog 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition suppressor of variegation 3-9 homolog 2

研究结论

Date Results Publications
2019-11-16 10:52:00 SUV39H2 elevation contributes to the progression of nasopharyngeal carcinoma via regulation of NRIP1 30709585
2019-07-27 11:35:00 Results discovered that SUV39H2 is a potential oncogene in lung adenocarcinoma, whose expression was elevated in tumor tissues. SUV39H2 could potentiate the tumorigenesis and invasion of lung adenocarcinoma cells, probably by repressing OPTN and STOM. 30348215
2019-05-18 12:17:00 Study revealed that high SUV39H2 expression positively predicted poor prognosis of CRC patients. Moreover, SUV39H2 promoted CRC proliferation in a SLIT1-dependent manner. 29458143
2019-02-02 10:47:00 Knockdown of SUV39H2 expression by specific siRNAs in human osteosarcoma cell lines markedly suppressed cancer cell growth and caused an increase in the population of cells in G1 phase and induced apoptosis. Overexpression of SUV39H2 promoted cell proliferation, which indicated that SUV39H2 may possess oncogenic activity in human osteosarcoma. 30542727
2017-12-16 10:50:00 Our finding unveils a novel autoregulatory mechanism of SUV39H2 through lysine automethylation 26988914

名称对应

Type IDs
Synonymous KMT1B
Gene
UniProtKB-ID: SUV92_HUMAN
UniprotKB: Q9H5I1
UniParc: UPI000002B461, UPI0000136177, UPI000002B462
EMBL: CH471072, AC069544, AL360083, AL834488, BC029360, CR457372, BC007754, AK027067
Ensembl: ENSG00000152455
KO: hsa:79723
Nucleutide sequences
EMBL-CDS: EAW86254.1, EAW86253.1, AAH29360.1, BAB15645.1, EAW86255.1, EAW86256.1, CAG33653.1, AAH07754.1, CAD39146.1
Ensembl_TRS: ENST00000313519, ENST00000378325, ENST00000354919
Protein sequencees
Ensembl_PRO: ENSP00000319208, ENSP00000346997, ENSP00000367576
RefSeq: NP_078946.1, NP_001180354.1, NP_001180353.1, NP_001180356.1, NP_001180355.1, XP_011517964.1, XP_006717566.1, XP_016872126.1
Others
UniRef100: UniRef100_Q9H5I1
UniRef90: UniRef90_Q9H5I1
UniRef50: UniRef50_Q9H5I1
UniGene: Hs.554883
CCDS: CCDS7104.1, CCDS53493.1, CCDS53494.1

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