| Type | Description |
|---|---|
| Definition | glycosyltransferase like domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-19 13:41:00 | MicroRNA-132 promotes neurons cell apoptosis and activates Tau phosphorylation by targeting GTDC-1 in Alzheimer's disease. | 31646584 |
| 2020-01-25 13:59:00 | Genomewide linkage scan by a targeted, high-density association scan for genetic variants enhancing persistently negative tuberculin skin test (PTST) in two independent Ugandan tuberculosis household cohorts. Association found with SNPs in neighboring genes ZEB2 and GTDC1 supported by both samples. Bioinformatic analysis suggests these variants may affect PTST- by regulating the histone deacetylase pathway. | 30100616 |
| 2017-09-23 10:13:00 | By deriving iPSCs from this patient and differentiating them into neural progenitor cells (NPCs) and neurons we dissected the disease process at the cellular level and observed defects in both NPCs and neuronal cells. We also showed that disruption of GTDC1 expression in wild type human NPCs and neurons showed a similar phenotype as patient's iPSCs | 28365779 |
| 2012-01-21 11:13:00 | The elevated expression of the Hmat-Xa gene (GTDC1) might serve as a candidate marker for colon adenocarcinoma. | 21821951 |
| 2010-06-30 22:05:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| Type | IDs |
|---|---|
| Synonymous | Hmat-Xa, mat-Xa |
| Gene |
UniProtKB-ID:
GTDC1_HUMAN
UniprotKB:
Q4AE62
UniParc:
UPI000022BC3B,
UPI00001BDA5B,
UPI0000EE2EDC,
UPI0000E07A7C,
UPI0000208C18,
UPI0000213EFA
EMBL:
AB597184,
AK021815,
BC061699,
CH471058,
BC017741,
AB201269,
AC010130,
AC009957,
AC010681,
AY281366,
AC016910,
AK291357
Ensembl:
ENSG00000121964
KO:
hsa:79712
|
| Nucleutide sequences |
EMBL-CDS:
BAK74843.1,
EAX11579.1,
EAX11581.1,
AAX93131.1,
BAE16560.1,
AAH17741.1,
EAX11580.1,
BAB13904.1,
EAX11583.1,
AAH61699.1,
AAQ16408.1,
BAF84046.1,
AAY14764.1,
EAX11584.1,
EAX11585.1,
EAX11582.1
Ensembl_TRS:
ENST00000344850,
ENST00000618778,
ENST00000409214,
ENST00000392871,
ENST00000542155,
ENST00000463875,
ENST00000241391,
ENST00000392869,
ENST00000392867
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000437964,
ENSP00000241391,
ENSP00000376608,
ENSP00000339750,
ENSP00000376606,
ENSP00000484990,
ENSP00000376610,
ENSP00000386581,
ENSP00000438323
RefSeq:
NP_001363257.1,
NP_001363253.1,
XP_011510157.1,
NP_001363261.1,
XP_016860407.1,
NP_001363250.1,
NP_001341290.1,
XP_016860428.1,
XP_016860446.1,
XP_024308912.1,
XP_016860437.1,
NP_001363237.1,
NP_001363248.1,
NP_001341283.1,
XP_024308913.1,
NP_001363246.1,
NP_078935.2,
NP_001341279.1,
NP_001363256.1,
NP_001006637.1,
NP_001363245.1,
XP_024308910.1,
XP_016860433.1,
NP_001341282.1,
XP_011510145.1,
XP_016860438.1,
XP_016860430.1,
NP_001363239.1,
XP_016860425.1,
XP_024308916.1,
XP_024308911.1,
XP_016860431.1,
NP_001341281.1,
NP_001363236.1,
NP_001363238.1,
XP_016860427.1,
NP_001341287.1,
NP_001341280.1,
XP_005263841.1,
XP_024308914.1,
XP_016860411.1,
NP_001363235.1,
XP_011510158.1,
NP_001363260.1,
NP_001363247.1,
XP_024308909.1,
NP_001271163.1,
NP_001158101.1,
NP_001363252.1,
XP_024308917.1,
NP_001341285.1,
XP_016860414.1,
XP_024308915.1,
NP_001341289.1,
NP_001363249.1,
NP_001341284.1,
XP_016860445.1,
XP_016860410.1,
NP_001363241.1,
XP_016860415.1,
NP_001363255.1,
NP_001363251.1,
NP_001271167.1,
NP_001363259.1,
NP_001363240.1,
NP_001341291.1,
XP_016860424.1,
XP_016860412.1,
NP_001363242.1,
NP_001363244.1,
NP_001363254.1,
XP_016860426.1,
XP_016860423.1,
NP_001271164.1,
XP_016860429.1,
NP_001363258.1,
XP_016860409.1,
NP_001363243.1,
NP_001271162.1
|
| Others |
UniRef100:
UniRef100_Q4AE62
UniRef90:
UniRef90_Q4AE62
UniRef50:
UniRef50_Q4AE62
UniGene:
Hs.44780,
Hs.724028,
Hs.724213
CCDS:
CCDS63029.1,
CCDS33300.1,
CCDS74582.1,
CCDS74583.1,
CCDS2185.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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Ensembl: {{protein.nucleotideEnsembl}} |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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