| Type | Description |
|---|---|
| Definition | importin 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 13:00:00 | Inhibiting Importin 4-mediated nuclear import of CEBPD enhances chemosensitivity by repression of PRKDC-driven DNA damage repair in cervical cancer. | 32661323 |
| 2020-09-19 16:24:00 | Importin-4 functions as a driving force in human primary gastric cancer. | 30861176 |
| 2017-05-20 14:34:00 | Importins, Impbeta, Kapbeta2, Imp4, Imp5, Imp7, Imp9, and Impalpha, show the H3 tail binding more tightly than the H4 tail. The H3 tail binds Kapbeta2 and Imp5 with KD values of 77 and 57 nm, respectively, and binds the other five Importins more weakly. | 27528606 |
| 2017-04-01 11:06:00 | Study identified a core region encompassing nt - 118 to + 108 of IPO4 gene that is necessary for its promoter activity. Transcription factors binding to this region were screened, resulting in the identification of two members of the Ets family, Ets-like transcription factor-1 and GA binding protein, which repress or activate its promoter activity, respectively. | 28254634 |
| 2010-10-30 11:14:00 | report a function of IPO4 and nuclear import in the Fanconi anemia pathway of DNA repair | 20805509 |
| Type | IDs |
|---|---|
| Synonymous | Imp4 |
| Gene |
UniProtKB-ID:
IPO4_HUMAN,
B3KT38_HUMAN
UniprotKB:
Q8TEX9,
B3KT38
UniParc:
UPI00003669A6,
UPI00003E5E37,
UPI000013CCB3
EMBL:
AF411122,
AK094897,
AK074743,
BC110804,
CH471078,
AK026991,
BC003690,
AL136295,
AK027871,
BX248267,
BC136759
Ensembl:
ENSG00000196497,
ENSG00000285248
KO:
hsa:79711
|
| Nucleutide sequences |
EMBL-CDS:
AAH03690.2,
EAW66078.1,
BAC11174.1,
BAB15616.1,
AAI10805.1,
AAL78660.1,
CAD62595.1,
AAI36760.1,
BAB55421.1,
BAG52950.1
Ensembl_TRS:
ENST00000354464,
ENST00000644546
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000494795,
ENSP00000346453
RefSeq:
NP_078934.3
|
| Others |
UniRef100:
UniRef100_B3KT38,
UniRef100_Q8TEX9
UniRef90:
UniRef90_W5QD14,
UniRef90_Q8TEX9
UniRef50:
UniRef50_Q8TEX9
UniGene:
Hs.411865
CCDS:
CCDS9616.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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