| Type | Description |
|---|---|
| Definition | leucine rich repeat kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-12-08 10:45:00 | data suggest that LRRK1 variant (rs2924835) and LRRK2 variants (rs34594498, rs34410987, and rs33949390) are not associated with essential tremor in this Han Chinese population | 29812962 |
| 2017-11-04 11:00:00 | LRRK1 plays a critical role in the regulation of bone mass in humans. | 27055475 |
| 2017-05-20 13:46:00 | A novel LRRK1 mutation has been identified in two siblings in an Indian family with osteosclerotic metaphyseal dysplasia. | 27829680 |
| 2016-03-05 10:35:00 | We find that LRRK1-mediated phosphorylation of CLIP-170 causes the accumulation of p150(Glued) (also known as DCTN1) a subunit of dynactin, at microtubule plus ends, thereby facilitating the migration of EGFR-containing endosomes. | 25413345 |
| 2015-10-24 11:27:00 | LRRK1 regulates mitotic spindle orientation downstream of PLK1 through CDK5RAP2-dependent centrosome maturation. | 26192437 |
| Type | IDs |
|---|---|
| Synonymous | RIPK6, Roco1 |
| Gene |
UniProtKB-ID:
LRRK1_HUMAN
UniprotKB:
Q38SD2
UniParc:
UPI0000D4C0AD,
UPI0000D4FE63
EMBL:
AK131075,
BC066655,
AK026772,
AC090907,
BC068080,
DQ013130,
AB058693,
AK130975
Ensembl:
ENSG00000154237
KO:
hsa:79705
|
| Nucleutide sequences |
EMBL-CDS:
AAH66655.1,
AAY67799.1,
BAB15547.1,
BAC85472.1,
BAC85125.1,
BAB47419.1,
AAH68080.1
Ensembl_TRS:
ENST00000388948,
ENST00000532029
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000373600,
ENSP00000433268
RefSeq:
XP_011520317.1,
XP_011520316.1,
XP_011520321.1,
XP_011520319.1,
XP_011520315.1,
XP_011520314.1,
XP_011520318.1,
XP_016878059.1,
XP_011520320.1,
NP_078928.3,
XP_005255036.1
|
| Others |
UniRef100:
UniRef100_Q38SD2
UniRef90:
UniRef90_Q38SD2
UniRef50:
UniRef50_Q38SD2
UniGene:
Hs.407918
CCDS:
CCDS42086.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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