| Type | Description |
|---|---|
| Definition | polypeptide N-acetylgalactosaminyltransferase 12 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-20 13:27:00 | The findings provide strong, independent evidence for the association of GALNT12 defects with CRC-susceptibility; underscoring implications for glycosylation pathway defects in CRC. | 29749045 |
| 2017-12-09 12:47:00 | LOH analyses, glycosylation pattern tests and case-control studies, our results did not support the role of c.907G>A, p.(D303N) as a high-penetrance risk allele for polyposis CRC | 29095867 |
| 2014-08-09 10:42:00 | Results rule out GALNT12 as a major high familial colorectal cancer susceptibility gene. Additional studies are required to provide further evidence about its role as a moderate/low susceptibility gene in familial aggregation of cancer. | 24115450 |
| 2014-07-26 11:30:00 | we integrated different computational tools to perform the in silico analysis of clinically significant mutations (nsSNPs/single amino acid change) at both functional and structural levels, found in human GALNT3, GALNT8, GALNT12, and GALNT13 genes. | 24038392 |
| 2012-09-29 11:04:00 | Inherited deleterious variants in GALNT12 are associated with CRC susceptibility. | 22461326 |
| Type | IDs |
|---|---|
| Synonymous | CRCS1, GalNAc-T12 |
| Gene |
UniProtKB-ID:
GLT12_HUMAN
UniprotKB:
Q8IXK2
UniParc:
UPI000004D295,
UPI0000072312
EMBL:
AB078146,
AK024865,
BC013945,
AL136084,
AJ132365
Ensembl:
ENSG00000119514
KO:
hsa:79695
|
| Nucleutide sequences |
EMBL-CDS:
CAC80100.2,
BAC07181.1,
BAB15027.1,
AAH13945.1
Ensembl_TRS:
ENST00000375011
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000364150
RefSeq:
XP_006717350.1,
XP_024303441.1,
XP_016870622.1,
NP_078918.3,
XP_011517322.1,
XP_011517320.1
|
| Others |
UniRef100:
UniRef100_Q8IXK2
UniRef90:
UniRef90_Q8IXK2
UniRef50:
UniRef50_Q8IXK2
UniGene:
Hs.47099
CCDS:
CCDS6737.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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