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79692 ZNF322

79692

ZNF322

zinc finger protein 322

protein-coding

Homo sapiens

基因描述

Type Description
Definition zinc finger protein 322

研究结论

Date Results Publications
2020-11-21 13:26:00 ZNF322A-mediated protein phosphorylation induces autophagosome formation through modulation of IRS1-AKT glucose uptake and HSP-elicited UPR in lung cancer. 32576196
2020-09-26 12:22:00 The ZNF322A-centered transcriptome promotes lung tumorigenesis and ZNF322A acts as a transcription suppressor of c-Myc to maintain lung cancer stem cell-like properties by shifting metabolism towards oxidative phosphorylation. 30258097
2020-02-29 10:47:00 results reveal a new mechanism of AKT signaling in promoting ZNF322A protein stability and transcriptional activity in lung cancer cell, xenograft, and clinical models 31399647
2018-10-27 10:28:00 Silencing ZNF322 recapitulated the cellular and molecular effects seen upon miR-4317 overexpression. 28880489
2017-10-28 13:03:00 Our results reveal a new mechanism of ZNF322A oncoprotein destruction regulated by the CK1delta/GSK3beta/FBXW7a axis. Deregulation of this signaling axis results in ZNF322A overexpression and promotes cancer progression 28581525

名称对应

Type IDs
Synonymous HCG12, ZNF322A, ZNF388, ZNF489
Gene
UniProtKB-ID: ZN322_HUMAN, A0A024QZZ4_HUMAN
UniprotKB: Q6U7Q0, A0A024QZZ4
UniParc: UPI00000437CC
EMBL: AK027046, BC074772, BC119669, AY376736, BC050425, AK290038, CH471087
Ensembl: ENSG00000181315
KO: hsa:79692
Nucleutide sequences
EMBL-CDS: AAH74772.1, AAI19670.1, AAQ85127.1, AAH50425.2, BAF82727.1, BAB15637.1, EAW55595.1, EAW55594.1, EAW55596.1
Gene_ORFName: hCG_1787373
Ensembl_TRS: ENST00000622479, ENST00000415922, ENST00000607204, ENST00000456172, ENST00000471278
Protein sequencees
Ensembl_PRO: ENSP00000419728, ENSP00000418897, ENSP00000478899, ENSP00000482607, ENSP00000483223
RefSeq: NP_078915.2, NP_001229727.1, NP_001229728.1, NP_001229726.1
Others
UniRef100: UniRef100_Q6U7Q0
UniRef90: UniRef90_Q6U7Q0
UniRef50: UniRef50_Q8BZ89
UniGene: Hs.126280, Hs.530271
CCDS: CCDS4617.1

全选

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