| Type | Description |
|---|---|
| Definition | structural maintenance of chromosomes 6 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 16:01:00 | The Smc5/6 Core Complex Is a Structure-Specific DNA Binding and Compacting Machine. | 33301731 |
| 2021-01-02 12:51:00 | Molecular Insights into the Architecture of the Human SMC5/6 Complex. | 32389690 |
| 2019-09-07 11:33:00 | Data suggest that SMC6 is not required for papillomavirus E2-mediated transcriptional activation, E1/E2-mediated transient replication, or differentiation-dependent amplification of viral DNA. However, a role for SMC5/6 complex was found in the papillomavirus genome maintenance. | 29848583 |
| 2018-11-24 12:20:00 | Study shows that the SMC5/6-hinge complex binds preferentially to ssDNA and that this interaction is affected by both 'latch' and 'hub' mutations, suggesting a key role for these unique features in controlling DNA association by the SMC5/6 complex. | 28134253 |
| 2017-11-18 10:56:00 | SMC5/6 knockdown rescued HBx-deficient hepatitis b virus replication in human hepatocytes. | 27626656 |
| Type | IDs |
|---|---|
| Synonymous | SMC-6, SMC6L1, hSMC6 |
| Gene |
UniProtKB-ID:
SMC6_HUMAN,
A0A2S1ZR87_HUMAN
UniprotKB:
Q96SB8,
A0A2S1ZR87
UniParc:
UPI0000073C3B,
UPI0000EADF55
EMBL:
CH471053,
BC032675,
AL832979,
AK292421,
AK025769,
AJ310551,
AL136544,
MF624758,
AC097377,
BC039828
Ensembl:
ENSG00000163029
KO:
hsa:79677
|
| Nucleutide sequences |
EMBL-CDS:
CAB66479.1,
BAB15236.1,
BAF85110.1,
AAX88851.1,
EAX00867.1,
EAX00868.1,
CAH56327.1,
CAC39248.1,
AAH32675.1,
AAH39828.1,
EAX00866.1,
AWK27960.1
Ensembl_TRS:
ENST00000448223,
ENST00000402989,
ENST00000351948
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000384539,
ENSP00000323439,
ENSP00000404092
RefSeq:
XP_011531410.1,
NP_001135758.1,
XP_016860402.1,
XP_011531409.1,
XP_016860404.1,
XP_016860403.1,
NP_078900.1,
XP_016860405.1
|
| Others |
UniRef100:
UniRef100_Q96SB8
UniRef90:
UniRef90_Q96SB8
UniRef50:
UniRef50_Q96SB8
UniGene:
Hs.526728
CCDS:
CCDS1690.1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| 1 |
University of Sussex |
4 |
| 2 |
University of Copenhagen |
3 |
| 3 |
University of Toronto |
3 |
| 4 |
The University of Texas Southwestern Medical Center |
3 |
| 5 |
Max Planck Institute of Molecular Cell Biology and Genetics |
2 |
| 排名 | 研究人员 | 文献 |
|---|---|---|
| 1 |
Patrick Ryan Potts |
5 |
| 2 |
Hongtao Yu |
4 |
| 3 |
Alan R Lehmann |
4 |
| 4 |
Richard M Myers |
3 |
| 5 |
Marco A Marra |
3 |