| Type | Description |
|---|---|
| Definition | FAST kinase domains 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-02 11:10:00 | Despite the fact that proteins of the FASTK family FASTKD1-5 share the same domains, they exhibit various-sometimes opposing-functions in almost all steps of mitochondrial RNA metabolism. | 29036396 |
| 2017-10-07 12:53:00 | Disruption of FASTKD1 increases ND3 mRNA level. Disrupting FASTKD1 and FASTKD4 decreases ND3 mRNA like depleting FASTKD4 alone. Each RAP domain of FASTK proteins contains a nuclease fold with a conserved aspartate residue at the putative active site. The RAP domain is essential for the function of the FASTK proteins, while the region upstream determines RNA targeting and protein localization. | 28335001 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
FAKD1_HUMAN,
D3DPC4_HUMAN,
Q05D57_HUMAN
UniprotKB:
Q53R41,
D3DPC4,
Q05D57
UniParc:
UPI000050BC4D,
UPI0000D49748,
UPI000013F861,
UPI000013F852
EMBL:
AK074302,
BC032687,
AB058703,
AK055892,
AK025554,
CH471058,
AC093899,
BC017950
Ensembl:
ENSG00000138399
KO:
hsa:79675
|
| Nucleutide sequences |
EMBL-CDS:
BAB85043.1,
AAH32687.1,
BAB47429.1,
AAY24118.1,
BAB15168.1,
BAB71037.1,
EAX11272.1,
EAX11274.1,
AAH17950.1
Gene_ORFName:
hCG_15217
Ensembl_TRS:
ENST00000453929,
ENST00000453153
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000403229,
ENSP00000400513
RefSeq:
XP_016860401.1,
NP_001308978.1,
XP_006712814.1,
NP_078898.3,
NP_001308975.1,
NP_001268405.1,
XP_016860400.1,
NP_001308977.1,
XP_006712813.1
|
| Others |
UniRef100:
UniRef100_D3DPC4,
UniRef100_Q05D57,
UniRef100_Q53R41
UniRef90:
UniRef90_Q05D57,
UniRef90_Q53R41
UniRef50:
UniRef50_Q53R41,
UniRef50_Q05D57
UniGene:
Hs.529276
CCDS:
CCDS63051.1,
CCDS33318.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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Ensembl: {{protein.nucleotideEnsembl}} |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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