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79671 NLRX1

79671

NLRX1

NLR family member X1

protein-coding

Homo sapiens

基因描述

Type Description
Definition NLR family member X1

研究结论

Date Results Publications
2021-02-20 13:33:00 MiR-423-5p Regulates Cells Apoptosis and Degradation via Nucleotide-Binding, Leucine-Rich Repeat Containing X1 (NLRX1) in Interleukin 1 beta (IL-1beta)-Induced Human Nucleus Pulposus Cells. 32467560
2021-01-02 12:48:00 HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING. 31874109
2020-02-08 10:45:00 mutations associated with multiple sclerosis 31525189
2020-02-08 10:37:00 NLRX1 regulates TNF-alpha-induced mitochondria-lysosomal crosstalk to maintain the invasive and metastatic potential of breast cancer cells. 30802640
2019-10-26 10:50:00 NLRX1 was downregulated in tumor tissue compared with adjacent normal liver tissue. Low tumor NLRX1 expression was identified as an independent indicator for HCC prognosis (recurrence: hazard ratio [HR] 1.87, 95% confidence interval [CI] 1.26-2.76, overall survival [OS] 2.26, 95% CI 1.44-3.56). NLRX1 over-expression (OE) significantly inhibited invasiveness ability and induced apoptosis in hepatocellular carcinoma cells. 29482578

名称对应

Type IDs
Synonymous CLR11.3, DLNB26, NOD26, NOD5, NOD9
Gene
UniProtKB-ID: NLRX1_HUMAN
UniprotKB: Q86UT6
UniParc: UPI0000161217, UPI000016196B
EMBL: BC110890, AB094095, AK291716, BK001111, AK095247, AK025131, EF452237, AK056454, AY245437, BC013199
Ensembl: ENSG00000160703
KO: hsa:79671
Nucleutide sequences
EMBL-CDS: BAG51714.1, BAG53014.1, BAF84405.1, AAI10891.1, BAC76049.1, DAA01244.1, BAB15075.1, ABO40480.1, AAP31240.1, AAH13199.3
Ensembl_TRS: ENST00000292199, ENST00000409991, ENST00000409109, ENST00000409265, ENST00000525863
Protein sequencees
Ensembl_PRO: ENSP00000292199, ENSP00000433442, ENSP00000386851, ENSP00000386858, ENSP00000387334
RefSeq: XP_016873783.1, XP_005271728.1, XP_005271726.1, NP_001269073.1, XP_006718967.1, XP_011541282.1, NP_078894.2, XP_005271729.1, XP_005271727.1, NP_001269287.1, NP_001269072.1
Others
UniRef100: UniRef100_Q86UT6
UniRef90: UniRef90_Q86UT6
UniRef50: UniRef50_Q86UT6
UniGene: Hs.524082
CCDS: CCDS8416.1

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