| Type | Description |
|---|---|
| Definition | U6 snRNA biogenesis phosphodiesterase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-21 12:06:00 | Here we investigate the molecular basis for the evolution of Usb1 CPDase activity. We examine the structure and function of Usb1 from Kluyveromyces marxianus, which shares 25 and 19% sequence identity to the S. cerevisiae and Homo sapiens orthologs of Usb1, respectively | 31832688 |
| 2019-07-06 10:30:00 | Data show that U6 snRNA phosphodiesterase (Usb1) removes 3' adenosines with 20-fold greater efficiency than uridines. | 30215753 |
| 2019-05-25 12:17:00 | A novel homozygous deletion of a 1-bp (c.161delC, p.P54RfsX60) in the C16orf57gene, was presumed to be causative of poikiloderma with neutropenia. The patient's asymptomatic consanguineous parents were heterozygotes for this mutation. | 29797650 |
| 2018-02-17 10:35:00 | this paper describes USB1 mutations characterized in four Moroccan patients out of three unrelated consanguinous families | 28353165 |
| 2017-12-30 12:50:00 | Data indicate the enzymatic activities and structures of yeast and human U6 RNA processing enzyme Usb1. | 28887445 |
| Type | IDs |
|---|---|
| Synonymous | C16orf57, HVSL1, Mpn1, PN, hUsb1 |
| Gene |
UniProtKB-ID:
USB1_HUMAN,
H3BNM8_HUMAN,
H3BN52_HUMAN,
A0A024R6V6_HUMAN
UniprotKB:
Q9BQ65,
H3BNM8,
H3BN52,
A0A024R6V6
UniParc:
UPI00001FF2DC,
UPI000041D9ED,
UPI0000E02B7A,
UPI0002466F7B,
UPI00000720EC
EMBL:
AK023216,
BC007774,
BC010099,
AK301494,
BC004415,
AC012182,
AK303121,
BC006291,
BC021554,
CH471092,
AC010543
Ensembl:
ENSG00000103005
KO:
hsa:79650
|
| Nucleutide sequences |
EMBL-CDS:
BAG64227.1,
AAH06291.1,
AAH10099.1,
BAB14469.1,
AAH07774.1,
AAH21554.1,
AAH04415.1,
BAG63005.1,
EAW82962.1,
EAW82964.1
Gene_ORFName:
hCG_16493
Ensembl_TRS:
ENST00000219281,
ENST00000539737,
ENST00000423271,
ENST00000561743,
ENST00000563149
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000219281,
ENSP00000446143,
ENSP00000409792,
ENSP00000454928,
ENSP00000454692
RefSeq:
NP_078874.2,
NP_001182231.1,
NP_001191840.1,
NP_001317498.1,
NP_001317497.1
|
| Others |
UniRef100:
UniRef100_Q9BQ65,
UniRef100_H3BN52
UniRef90:
UniRef90_H3BN52,
UniRef90_Q9BQ65
UniRef50:
UniRef50_Q9BQ65,
UniRef50_Q9BQ65-3
UniGene:
Hs.408702
CCDS:
CCDS55997.1,
CCDS55998.1,
CCDS10791.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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