| Type | Description |
|---|---|
| Definition | MAP7 domain containing 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 10:39:00 | MAP7 proteins are microtubule-tethered kinesin-1 activators, with which the motor transiently interacts as it moves along microtubules. | 30770434 |
| 2017-08-05 11:54:00 | Mdp3 (also known as MAP7D3) forms a complex with DDA3 (also known as PSRC1) and controls spindle dynamics at the minus end of Microtubuless by inhibiting DDA3-mediated Kif2a recruitment to the spindle. | 27284004 |
| 2016-04-02 10:10:00 | the amino-terminal region mediated the interaction of Mdp3 with histone deacetylase 6 (HDAC6), in addition to its association with tubulin and microtubules. | 24614595 |
| 2015-10-31 10:23:00 | Results have identified a new microtubule binding region in MAP7D3, formed by the conserved MAP7 domain and the C-terminal tail, which can bind to microtubules and promote their assembly and stability. | 24927501 |
| 2015-04-25 11:06:00 | A critical role for Mdp3 in the growth and metastasis of breast cancer. | 25161703 |
| Type | IDs |
|---|---|
| Synonymous | MDP3 |
| Gene |
UniProtKB-ID:
MA7D3_HUMAN
UniprotKB:
Q8IWC1
UniParc:
UPI00001C207C,
UPI0001CB27C6,
UPI000013C756,
UPI00015C73E9
EMBL:
BC040518,
AL078638,
BC064350,
AK022711,
CH471150,
AL832120,
AK301478
Ensembl:
ENSG00000129680
KO:
hsa:79649
|
| Nucleutide sequences |
EMBL-CDS:
AAH40518.1,
BAB14195.1,
BAG62994.1,
AAH64350.1,
EAW88475.1
Ensembl_TRS:
ENST00000370663,
ENST00000370661,
ENST00000316077
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000359695,
ENSP00000318086,
ENSP00000359697
RefSeq:
XP_005262529.1,
NP_001166988.1,
XP_024308216.1,
NP_078873.2,
XP_016885332.1,
NP_001166987.1
|
| Others |
UniRef100:
UniRef100_Q8IWC1
UniRef90:
UniRef90_Q8IWC1
UniRef50:
UniRef50_Q8IWC1
UniGene:
Hs.446275
CCDS:
CCDS44004.1,
CCDS55508.1,
CCDS55509.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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