| Type | Description |
|---|---|
| Definition | microcephalin 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:27:00 | MCPH1 Lack of Function Enhances Mitotic Cell Sensitivity Caused by Catalytic Inhibitors of Topo II. | 32276518 |
| 2020-12-19 13:45:00 | Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly. | 33203878 |
| 2020-12-12 13:23:00 | Analysis of the ""centrosome-ome"" identifies MCPH1 deletion as a cause of centrosome amplification in human cancer. | 32681070 |
| 2020-10-31 13:17:00 | Microcephaly family protein MCPH1 stabilizes RAD51 filaments. | 32735676 |
| 2020-05-23 11:55:00 | results demonstrate that, although MCPH1 function is dispensable for activation and maintenance of the decatenation checkpoint, it is required for the adaptive response that bypasses the topoisomerase II inhibition----mediated G2 arrest. | 30964711 |
| Type | IDs |
|---|---|
| Synonymous | BRIT1, MCT |
| Gene |
UniProtKB-ID:
MCPH1_HUMAN
UniprotKB:
Q8NEM0
UniParc:
UPI000020FF7E,
UPI0001C4E0EF,
UPI000020FF7B
EMBL:
AF287957,
KC877206,
AC016065,
BC030702,
KC877207,
AK301702,
AX087870,
BK004076,
AC018398,
AK022909
Ensembl:
ENSG00000147316,
ENSG00000285262
KO:
hsa:79648
|
| Nucleutide sequences |
EMBL-CDS:
AAH30702.2,
CAC34661.1,
BAG63174.1,
BAB14304.1,
DAA04567.1
Ensembl_TRS:
ENST00000646478,
ENST00000519480,
ENST00000647051,
ENST00000522905,
ENST00000344683,
ENST00000643429
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000496505,
ENSP00000430768,
ENSP00000493874,
ENSP00000430962,
ENSP00000342924,
ENSP00000494584
RefSeq:
XP_011533062.1,
XP_011533060.1,
XP_016869321.1,
NP_001308972.2,
XP_011533058.1,
XP_016869318.1,
NP_001308974.2,
NP_001166045.2,
NP_001350909.1,
XP_011533057.1,
XP_016869320.1,
XP_011533059.1,
NP_001350908.1,
NP_001308971.2,
XP_016869322.1,
NP_078872.3,
NP_001166046.1,
XP_011533061.1
|
| Others |
UniRef100:
UniRef100_Q8NEM0
UniRef90:
UniRef90_Q8NEM0
UniRef50:
UniRef50_Q8NEM0
UniGene:
Hs.656769,
Hs.708770
CCDS:
CCDS43689.1,
CCDS55191.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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