| Type | Description |
|---|---|
| Definition | ribonuclease H2 subunit B |
| Date | Results | Publications |
|---|---|---|
| 2019-12-07 10:06:00 | AGS mutations in this cluster impair the interaction of RNase H2 with several members of the CoREST chromatin-silencing complex that include the histone deacetylase HDAC2 and the demethylase KDM1A, the transcriptional regulators RCOR1 and GTFII-I as well as ZMYM3, an MYM-type zinc finger protein. | 30889214 |
| 2018-06-16 12:05:00 | Results implicate rare variants in the Aicardi-Goutieres syndrome genes ADAR and RNASEH2B and a type I interferon signature in glioma and prostate carcinoma risk and tumorigenesis, consistent with a genetic basis underlying inflammation-driven malignant transformation in glioma and prostate carcinoma development. | 29030706 |
| 2017-02-25 10:21:00 | This study reviewed that Neurologic Phenotypes Associated with Mutations in RNASEH2B in patients with Aicardi-Goutieres Syndrome. | 27643693 |
| 2016-03-12 10:18:00 | Aicardi-Goutieres syndrome 2 is caused by mutations in the ribonuclease H2 subunit B gene RNASEH2B. | 25906927 |
| 2015-07-25 11:30:00 | RNase H2 complex is assembled in the cytosol and imported into the nucleus in an RNase H2B-dependent manner. | 24986920 |
| Type | IDs |
|---|---|
| Synonymous | AGS2, DLEU8 |
| Gene |
UniProtKB-ID:
RNH2B_HUMAN,
A0A2R8Y883_HUMAN,
Q8N451_HUMAN
UniprotKB:
Q5TBB1,
A0A2R8Y883,
Q8N451
UniParc:
UPI000013CFE7,
UPI0005D01C08,
UPI0000D4DA79,
UPI0000070E04
EMBL:
BC036744,
AY764036,
BC001397,
CH471075,
AL160157,
BC007332,
BC005088,
AK021774,
AK223340,
BC010174,
AL137881
Ensembl:
ENSG00000136104
KO:
hsa:79621
|
| Nucleutide sequences |
EMBL-CDS:
AAH05088.1,
EAX08864.1,
AAH01397.1,
AAH07332.1,
AAX13343.1,
AAH10174.1,
BAB13892.1,
BAD97060.1,
AAH36744.1
Ensembl_TRS:
ENST00000336617,
ENST00000422660,
ENST00000645990
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000337623,
ENSP00000389877,
ENSP00000496571
RefSeq:
XP_011533535.1,
XP_006719930.1,
XP_011533533.1,
XP_011533531.1,
XP_016876236.1,
NP_001135751.1,
XP_011533532.1,
NP_078846.2
|
| Others |
UniRef100:
UniRef100_Q8N451,
UniRef100_A0A2R8Y883,
UniRef100_Q5TBB1
UniRef90:
UniRef90_Q5TBB1,
UniRef90_G3QFF7
UniRef50:
UniRef50_Q5TBB1
UniGene:
Hs.306291
CCDS:
CCDS45047.1,
CCDS9425.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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