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79603 CERS4

79603

CERS4

ceramide synthase 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition ceramide synthase 4

研究结论

Date Results Publications
2018-08-04 11:19:00 nine SNPs in the ceramide synthase 4 (CERS4) region were associated with circulating C23:0 levels (adjusted P<5x10-2) 29738550
2016-08-20 10:23:00 These results suggest that the phosphorylation of ceramide synthases may be a key regulatory point in the control of the distribution and levels of sphingolipids of various acyl-chain lengths. 26887952
2015-08-01 10:58:00 mRNA level of CerS4 is higher in cancerous cell lines and decreases following the induction of apoptosis. 25779024
2014-01-18 11:23:00 Co-expression of CerS2 with CerS4/CerS6 reversed the inhibitory effect of long chain ceramides on cell proliferation and the induction of apoptosis. we detected no effect on cell proliferation. 23538298
2012-01-14 10:46:00 The linkage and association of phospholipid transfer protein activity to LASS4 were studied. 21757428

名称对应

Type IDs
Synonymous LASS4, Trh1
Gene
UniProtKB-ID: CERS4_HUMAN, Q53HF9_HUMAN
UniprotKB: Q9HA82, Q53HF9
UniParc: UPI000013CCFB, UPI000050A711
EMBL: AK022151, AK222621, CH471139, BC009828, AC022146
Ensembl: ENSG00000090661
KO: hsa:79603
Nucleutide sequences
EMBL-CDS: BAB13972.1, EAW68941.1, EAW68945.1, EAW68940.1, AAH09828.1, EAW68942.1, BAD96341.1
Ensembl_TRS: ENST00000251363, ENST00000559450
Protein sequencees
Ensembl_PRO: ENSP00000251363, ENSP00000453509
RefSeq: XP_016882792.1, XP_011526592.1, XP_011526593.1, XP_011526597.1, XP_011526595.1, XP_016882794.1, NP_078828.2, XP_011526596.1, XP_024307487.1, XP_011526594.1, XP_016882793.1
Others
UniRef100: UniRef100_Q53HF9, UniRef100_Q9HA82
UniRef90: UniRef90_Q9HA82
UniRef50: UniRef50_Q9HA82
UniGene: Hs.515111
CCDS: CCDS12197.1

全选

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