| Type | Description |
|---|---|
| Definition | mitochondrial E3 ubiquitin protein ligase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:17:00 | Mitochondrial MUL1 E3 ubiquitin ligase regulates Hypoxia Inducible Factor (HIF-1alpha) and metabolic reprogramming by modulating the UBXN7 cofactor protein. | 32005965 |
| 2020-07-04 12:14:00 | These results provide a molecular basis for the novel recognition mechanism of the p53-transactivation domain substrate by the MUL1-RING domain. | 31235254 |
| 2020-06-13 10:32:00 | The three-dimensional structures of MUL1-RING and of its complex with the cognate E2 enzyme has been determined. | 31929179 |
| 2019-05-25 11:34:00 | The allele T in the rs529974(+) MUL1 gene was susceptible to Parkinson's disease | 30793286 |
| 2019-03-23 11:06:00 | negatively regulates lysosomal activity through ubiquitination of MUL1 in head and neck cancer | 29260979 |
| Type | IDs |
|---|---|
| Synonymous | C1orf166, GIDE, MAPL, MULAN, RNF218 |
| Gene |
UniProtKB-ID:
MUL1_HUMAN,
A1PUM0_HUMAN
UniprotKB:
Q969V5,
A1PUM0
UniParc:
UPI00000361FC
EMBL:
EU935008,
AL833889,
CH471134,
AL391357,
BC010101,
AB097015,
BC014010,
AK022937
Ensembl:
ENSG00000090432
KO:
hsa:79594
|
| Nucleutide sequences |
EMBL-CDS:
AAH10101.1,
BAC77368.1,
AAH14010.1,
BAB14317.1,
ACH72645.1,
CAD38745.1,
EAW94927.1,
EAW94926.1
Gene_ORFName:
hCG_38180
Ensembl_TRS:
ENST00000264198
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000264198
RefSeq:
XP_011540439.1,
NP_078820.2
|
| Others |
UniRef100:
UniRef100_Q969V5
UniRef90:
UniRef90_Q969V5
UniRef50:
UniRef50_Q969V5
UniGene:
Hs.10101
CCDS:
CCDS208.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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